𝕏

Task 54274323

Name HuVeMOp_20240622105159185157_ORdGradInc_k_23-Coppini_2000-conf_623_1
Workunit 25769295
Created 22 Jun 2024, 8:55:43 UTC
Sent 22 Jun 2024, 12:05:54 UTC
Report deadline 25 Jun 2024, 12:05:54 UTC
Received 22 Jun 2024, 17:04:55 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 231095
Run time 58 min 26 sec
CPU time 45 min 53 sec
Validate state Valid
Credit 44.17
Device peak FLOPS 4.70 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.69 MB
Peak swap size 6.23 MB
Peak disk usage 0.63 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240622105159185157_ORdGradInc_k_23-Coppini_2000-conf_623.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240622105159185157_ORdGradInc_k_23-Coppini_2000-conf_623_1_r2100797178_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240622105159185157_ORdGradInc_k_23-Coppini_2000-conf_623_1_r2100797178_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 115.912644
     * GNaL_b in INaL: 0.016612
     * Gto_b in Ito: 0.068602
     * PCa_b in ICaL: 0.000078
     * GKr_b in IKr: 0.030777
     * GKs_b in IKs: 0.002193
     * GK1_b in IK1: 0.129500
     * Gncx_b in INaCa_i: 0.000959
     * Pnak_b in INaK: 55.098534
     * GKb_b in IKb: 0.003423
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.074745
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 9825321, states[0] = -94.735479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 18985674, states[0] = -94.689724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33814063, states[0] = -94.665447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 46739318, states[0] = -94.656390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 61085872, states[0] = 13.424713, states[40]= 0.005015
Saving checkpoint... 
Iteration: 75478491, states[0] = -94.609638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 89302630, states[0] = -94.403807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 102213322, states[0] = -71.531448, states[40]= 0.000004
Saving checkpoint... 
Iteration: 117156251, states[0] = -24.702289, states[40]= 0.003035
Saving checkpoint... 
Iteration: 131366783, states[0] = -94.517395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 145262364, states[0] = -94.281710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 158939865, states[0] = -94.640105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 164056013, states[0] = 23.683396, states[40]= 0.003455
Saving checkpoint... 
Iteration: 169039050, states[0] = 28.101108, states[40]= 0.002473
Saving checkpoint... 
Iteration: 182666491, states[0] = -94.641220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 196768301, states[0] = -94.643324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 210393480, states[0] = -94.546328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 224274294, states[0] = -94.320664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 237068969, states[0] = 19.696443, states[40]= 0.004269
Saving checkpoint... 
Iteration: 242127778, states[0] = -6.549121, states[40]= 0.003579
Saving checkpoint... 
Iteration: 255725373, states[0] = -94.642710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 265265029, states[0] = -94.290080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 274681152, states[0] = -94.641377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 279324358, states[0] = -94.447315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 288492220, states[0] = -94.609274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 296245672, states[0] = -94.121092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 305670822, states[0] = -94.640812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311394976, states[0] = -94.547419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 324586754, states[0] = -94.632858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 338364035, states[0] = -94.511938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 348101394, states[0] = 7.083503, states[40]= 0.005284
Saving checkpoint... 
Iteration: 360976888, states[0] = -94.637709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 370942862, states[0] = -94.638862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 377065106, states[0] = 20.951928, states[40]= 0.004042
Saving checkpoint... 
Iteration: 385310136, states[0] = -94.416871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 390900600, states[0] = -94.640174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 405162566, states[0] = -28.495417, states[40]= 0.002664
Saving checkpoint... 
Iteration: 419743944, states[0] = -94.642577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 429661713, states[0] = -94.640090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 434862323, states[0] = -94.641163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 448305406, states[0] = -94.405741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 453444006, states[0] = -94.585402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 461434560, states[0] = -94.579356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 470944646, states[0] = -94.638638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 476184030, states[0] = -43.492999, states[40]= 0.000464
Saving checkpoint... 
Iteration: 481895140, states[0] = -94.640189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 493941842, states[0] = -94.638695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 502901658, states[0] = -94.639961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 516033572, states[0] = 29.298042, states[40]= 0.002277
Saving checkpoint... 
Iteration: 525043614, states[0] = 27.012346, states[40]= 0.002696
Saving checkpoint... 
Iteration: 533524739, states[0] = -94.619575, states[40]= 0.000000
Saving checkpoint... 
Iteration: 547289415, states[0] = -94.364450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 556072828, states[0] = 18.391872, states[40]= 0.004476
Saving checkpoint... 
Iteration: 561010033, states[0] = 31.044209, states[40]= 0.047539
Saving checkpoint... 
Iteration: 570934330, states[0] = -94.638821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 576621150, states[0] = -94.636677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 586352324, states[0] = -94.495017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 589663642, states[0] = -94.639946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 598964622, states[0] = -94.637752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 614036996, states[0] = 28.573530, states[40]= 0.002391
Saving checkpoint... 
Iteration: 623600743, states[0] = -94.634290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 628228559, states[0] = -89.401475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 633841079, states[0] = -94.641343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 642227977, states[0] = -88.881620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 655742345, states[0] = -94.642188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 665322007, states[0] = -94.441938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 680586733, states[0] = -94.632272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 686054727, states[0] = 24.059645, states[40]= 0.003372
Saving checkpoint... 
Iteration: 700647376, states[0] = -94.638724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 710537239, states[0] = -94.622592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 725547626, states[0] = -94.625013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 735152151, states[0] = -22.123028, states[40]= 0.002813
Saving checkpoint... 
Iteration: 749376758, states[0] = -94.527156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 758718577, states[0] = -94.641704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 769504108, states[0] = -94.612789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 783683223, states[0] = -94.640601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 791269451, states[0] = -94.304090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 800914164, states[0] = -94.639104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 810654570, states[0] = -94.639042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 816356658, states[0] = -94.500987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 821520848, states[0] = -94.618005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 822934061, states[0] = -94.638430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 833680934, states[0] = -94.640424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 843010603, states[0] = 31.043561, states[40]= 0.039570
Saving checkpoint... 
Iteration: 847372444, states[0] = -94.521836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 856092903, states[0] = 10.735642, states[40]= 0.005191
Saving checkpoint... 
Iteration: 867702996, states[0] = -94.641158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 869934532, states[0] = -94.638340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 871759259, states[0] = -94.641919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 886718201, states[0] = -94.641493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 887683760, states[0] = -94.640458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 902477211, states[0] = -94.602048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 912268806, states[0] = -94.301776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 921117796, states[0] = -0.841962, states[40]= 0.004769
Saving checkpoint... 
Iteration: 930596366, states[0] = -94.633232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 940888581, states[0] = -94.639650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 950544403, states[0] = -94.623924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 964453342, states[0] = -94.590039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 978953798, states[0] = -94.637521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 989129383, states[0] = -7.536039, states[40]= 0.003338
Saving checkpoint... 
Iteration: 1003118575, states[0] = -1.258061, states[40]= 0.004704
Saving checkpoint... 
Iteration: 1012477189, states[0] = -94.601864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1036353079, states[0] = -94.495423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1050876753, states[0] = -94.639806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1057301305, states[0] = -94.394790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1071071274, states[0] = 18.924979, states[40]= 0.004395
Saving checkpoint... 
Iteration: 1080500736, states[0] = -94.611120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1090806942, states[0] = -94.641233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1104697768, states[0] = -94.640625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1114444051, states[0] = -94.584377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1129383209, states[0] = -94.533873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1141404722, states[0] = -94.555181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1155147232, states[0] = -19.076760, states[40]= 0.002293
Saving checkpoint... 
Iteration: 1164980461, states[0] = -94.636299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1179736175, states[0] = -94.641300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1189657852, states[0] = -94.638649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1203413454, states[0] = -94.562541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1218092329, states[0] = 10.973720, states[40]= 0.005179
Saving checkpoint... 
Iteration: 1227205525, states[0] = -63.117423, states[40]= 0.000019
Saving checkpoint... 
Iteration: 1239786052, states[0] = -94.641232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253998304, states[0] = -94.635522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1259304424, states[0] = -94.402087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1274742697, states[0] = -94.641209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1285674910, states[0] = -94.639432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1295807967, states[0] = -94.640893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1306199308, states[0] = -57.159203, states[40]= 0.000054
Saving checkpoint... 
Iteration: 1314559551, states[0] = -94.626586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1324373420, states[0] = -94.522264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1338640656, states[0] = -94.637207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1352134602, states[0] = -10.869719, states[40]= 0.002589
Saving checkpoint... 
Iteration: 1357234333, states[0] = -92.712998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1365360412, states[0] = -94.505383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1380148780, states[0] = -20.046187, states[40]= 0.002452
Saving checkpoint... 
Iteration: 1387998922, states[0] = -94.635287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1402253890, states[0] = -94.237423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1412378582, states[0] = -94.528218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1420530732, states[0] = -94.619799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1430360010, states[0] = -94.504724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1444275957, states[0] = -94.323681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1458977617, states[0] = -94.635933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1469984946, states[0] = -94.635656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1484385458, states[0] = -94.535753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1485751639, states[0] = -94.640927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1495909593, states[0] = -94.638143, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.511008
 - CaMKt in component CaMK (millimolar): 0.004503
 - cass in component intracellular_ions (millimolar): 0.000086
 - nai in component intracellular_ions (millimolar): 6.757607
 - nass in component intracellular_ions (millimolar): 6.757697
 - ki in component intracellular_ions (millimolar): 145.153230
 - kss in component intracellular_ions (millimolar): 145.153214
 - cansr in component intracellular_ions (millimolar): 1.606585
 - cajsr in component intracellular_ions (millimolar): 1.605392
 - cai in component intracellular_ions (millimolar): 0.000088
 - m in component INa (dimensionless): 0.003764
 - hf in component INa (dimensionless): 0.873051
 - hs in component INa (dimensionless): 0.873052
 - j in component INa (dimensionless): 0.873060
 - hsp in component INa (dimensionless): 0.712901
 - jp in component INa (dimensionless): 0.873064
 - mL in component INaL (dimensionless): 0.000053
 - hL in component INaL (dimensionless): 0.718512
 - hLp in component INaL (dimensionless): 0.505304
 - a in component Ito (dimensionless): 0.000640
 - iF in component Ito (dimensionless): 0.999860
 - iS in component Ito (dimensionless): 0.880562
 - ap in component Ito (dimensionless): 0.000326
 - iFp in component Ito (dimensionless): 0.999860
 - iSp in component Ito (dimensionless): 0.921717
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.966155
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002842
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.113587
 - xs1 in component IKs (dimensionless): 0.152400
 - xs2 in component IKs (dimensionless): 0.000092
 - xk1 in component IK1 (dimensionless): 0.997438
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
17:31:26 (8044): called boinc_finish(0)

</stderr_txt>
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