𝕏

Task 54242567

Name HuVeMOp_20240622023434439622_ORdGradInc_k_23-TESZT_Block_Kr_70-conf_551_1
Workunit 25755015
Created 22 Jun 2024, 0:45:04 UTC
Sent 22 Jun 2024, 8:29:10 UTC
Report deadline 25 Jun 2024, 8:29:10 UTC
Received 22 Jun 2024, 23:08:01 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 223137
Run time 2 hours 12 min 42 sec
CPU time 2 hours 12 min 42 sec
Validate state Valid
Credit 43.20
Device peak FLOPS 2.90 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.19 MB
Peak swap size 6.23 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240622023434439622_ORdGradInc_k_23-TESZT_Block_Kr_70-conf_551.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240622023434439622_ORdGradInc_k_23-TESZT_Block_Kr_70-conf_551_1_r537273_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240622023434439622_ORdGradInc_k_23-TESZT_Block_Kr_70-conf_551_1_r537273_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 141.475340
     * GNaL_b in INaL: 0.003953
     * Gto_b in Ito: 0.083569
     * PCa_b in ICaL: 0.000082
     * GKr_b in IKr: 0.009923
     * GKs_b in IKs: 0.001676
     * GK1_b in IK1: 0.137721
     * Gncx_b in INaCa_i: 0.000935
     * Pnak_b in INaK: 75.455288
     * GKb_b in IKb: 0.004185
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.028685
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 9787602, states[0] = -94.952611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 20263367, states[0] = -92.880678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 30970309, states[0] = -94.990673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 41952778, states[0] = -94.950943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 52461187, states[0] = -94.934834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 63107609, states[0] = 1.376339, states[40]= 0.005205
Saving checkpoint... 
Iteration: 74491057, states[0] = -94.921105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 85914992, states[0] = -94.870768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97116029, states[0] = -1.518096, states[40]= 0.004730
Saving checkpoint... 
Iteration: 108160497, states[0] = -21.216398, states[40]= 0.004441
Saving checkpoint... 
Iteration: 119187859, states[0] = -30.762197, states[40]= 0.003026
Saving checkpoint... 
Iteration: 129805693, states[0] = -94.647305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 141275286, states[0] = -75.962428, states[40]= 0.000003
Saving checkpoint... 
Iteration: 152491512, states[0] = -94.892330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 163663478, states[0] = -21.876456, states[40]= 0.004589
Saving checkpoint... 
Iteration: 174327409, states[0] = -94.734265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 185372498, states[0] = -94.804589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 196022571, states[0] = 29.834546, states[40]= 0.004135
Saving checkpoint... 
Iteration: 207236627, states[0] = -50.362484, states[40]= 0.000212
Saving checkpoint... 
Iteration: 217489780, states[0] = -94.887744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 228016492, states[0] = 30.588577, states[40]= 0.008926
Saving checkpoint... 
Iteration: 239060604, states[0] = 19.118951, states[40]= 0.004883
Saving checkpoint... 
Iteration: 250487608, states[0] = -94.886313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 261590894, states[0] = 8.761122, states[40]= 0.005491
Saving checkpoint... 
Iteration: 272475344, states[0] = -94.881071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 282994215, states[0] = -94.888462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 294126154, states[0] = -5.458321, states[40]= 0.003878
Saving checkpoint... 
Iteration: 304680326, states[0] = -27.561143, states[40]= 0.003942
Saving checkpoint... 
Iteration: 315873841, states[0] = -94.803828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 326834352, states[0] = -94.744295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 337642014, states[0] = -12.973038, states[40]= 0.002581
Saving checkpoint... 
Iteration: 348019304, states[0] = 30.332372, states[40]= 0.005574
Saving checkpoint... 
Iteration: 358708033, states[0] = -37.895474, states[40]= 0.001313
Saving checkpoint... 
Iteration: 369999669, states[0] = -94.890009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 380601022, states[0] = 4.991930, states[40]= 0.005386
Saving checkpoint... 
Iteration: 391883319, states[0] = -94.814600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 402884978, states[0] = -94.816392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 413854062, states[0] = -94.776740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 424722748, states[0] = -44.038227, states[40]= 0.000563
Saving checkpoint... 
Iteration: 435698585, states[0] = -34.197586, states[40]= 0.002074
Saving checkpoint... 
Iteration: 446910594, states[0] = -94.840765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 457569672, states[0] = 16.179399, states[40]= 0.005217
Saving checkpoint... 
Iteration: 468755233, states[0] = -59.564387, states[40]= 0.000044
Saving checkpoint... 
Iteration: 479867896, states[0] = -94.795894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 491093867, states[0] = 7.675635, states[40]= 0.005478
Saving checkpoint... 
Iteration: 501926282, states[0] = -94.852753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 513183006, states[0] = -28.494148, states[40]= 0.003680
Saving checkpoint... 
Iteration: 524554313, states[0] = 21.100008, states[40]= 0.004583
Saving checkpoint... 
Iteration: 535487324, states[0] = -94.885150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 546468838, states[0] = -94.877297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 557762431, states[0] = -63.904863, states[40]= 0.000021
Saving checkpoint... 
Iteration: 569193288, states[0] = -32.205734, states[40]= 0.002594
Saving checkpoint... 
Iteration: 580191301, states[0] = -31.473117, states[40]= 0.002802
Saving checkpoint... 
Iteration: 591331806, states[0] = -94.738898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 601872748, states[0] = -94.801765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 613015586, states[0] = 30.646839, states[40]= 0.010877
Saving checkpoint... 
Iteration: 624125432, states[0] = -5.121676, states[40]= 0.003954
Saving checkpoint... 
Iteration: 635099686, states[0] = 5.500065, states[40]= 0.005411
Saving checkpoint... 
Iteration: 646050183, states[0] = 22.373000, states[40]= 0.004369
Saving checkpoint... 
Iteration: 657495021, states[0] = -94.887736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 668859577, states[0] = -94.784197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 680322603, states[0] = -94.719901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 691069028, states[0] = 16.393343, states[40]= 0.005198
Saving checkpoint... 
Iteration: 691180019, states[0] = -27.448611, states[40]= 0.003972
Saving checkpoint... 
Iteration: 701289966, states[0] = -91.312388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 707193457, states[0] = -32.268165, states[40]= 0.002577
Saving checkpoint... 
Iteration: 717773396, states[0] = -72.627038, states[40]= 0.000005
Saving checkpoint... 
Iteration: 728837684, states[0] = -94.749339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 740109865, states[0] = 1.540054, states[40]= 0.005115
Saving checkpoint... 
Iteration: 751359072, states[0] = -94.783298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 762541344, states[0] = 25.046589, states[40]= 0.003927
Saving checkpoint... 
Iteration: 773823931, states[0] = -94.722650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 785095108, states[0] = 7.216396, states[40]= 0.005468
Saving checkpoint... 
Iteration: 796428144, states[0] = -94.853417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 807913882, states[0] = -94.842667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 819248823, states[0] = -56.152183, states[40]= 0.000080
Saving checkpoint... 
Iteration: 830818339, states[0] = -94.708849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 842242124, states[0] = -52.848005, states[40]= 0.000140
Saving checkpoint... 
Iteration: 853599775, states[0] = 5.466566, states[40]= 0.005409
Saving checkpoint... 
Iteration: 865100242, states[0] = 5.289465, states[40]= 0.005401
Saving checkpoint... 
Iteration: 876193925, states[0] = -32.441718, states[40]= 0.002529
Saving checkpoint... 
Iteration: 887478874, states[0] = -94.880977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 898563251, states[0] = 18.279752, states[40]= 0.004995
Saving checkpoint... 
Iteration: 909863703, states[0] = -94.789379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 921361229, states[0] = -94.785956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 932901708, states[0] = -94.831918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 944438218, states[0] = -94.859785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 955971942, states[0] = -94.877814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 967410009, states[0] = -94.839124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 979028627, states[0] = 28.569880, states[40]= 0.003598
Saving checkpoint... 
Iteration: 990653595, states[0] = -18.050038, states[40]= 0.003401
Saving checkpoint... 
Iteration: 1002008838, states[0] = 31.037470, states[40]= 0.072607
Saving checkpoint... 
Iteration: 1013601028, states[0] = 4.990632, states[40]= 0.005386
Saving checkpoint... 
Iteration: 1024883124, states[0] = -94.812973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1036158301, states[0] = -19.865267, states[40]= 0.004080
Saving checkpoint... 
Iteration: 1047893057, states[0] = -94.823386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1059548821, states[0] = 22.789849, states[40]= 0.004298
Saving checkpoint... 
Iteration: 1071289462, states[0] = -90.942405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1082999357, states[0] = -94.888313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1094240605, states[0] = -52.122821, states[40]= 0.000158
Saving checkpoint... 
Iteration: 1105464341, states[0] = -94.873932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1116719242, states[0] = -42.529074, states[40]= 0.000700
Saving checkpoint... 
Iteration: 1128008251, states[0] = 31.217032, states[40]= 0.087098
Saving checkpoint... 
Iteration: 1139693460, states[0] = -32.268566, states[40]= 0.002577
Saving checkpoint... 
Iteration: 1151121506, states[0] = -3.354437, states[40]= 0.004337
Saving checkpoint... 
Iteration: 1162320774, states[0] = -94.714514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1173809949, states[0] = -94.668060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1184909148, states[0] = -94.837917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1185861977, states[0] = -94.786408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1196510331, states[0] = 30.811437, states[40]= 0.045890
Saving checkpoint... 
Iteration: 1207071510, states[0] = 15.566022, states[40]= 0.005268
Saving checkpoint... 
Iteration: 1217940376, states[0] = -94.860530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1228879770, states[0] = -94.808740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1239753559, states[0] = -58.638928, states[40]= 0.000052
Saving checkpoint... 
Iteration: 1250718432, states[0] = -42.184386, states[40]= 0.000735
Saving checkpoint... 
Iteration: 1261718545, states[0] = -42.232322, states[40]= 0.000730
Saving checkpoint... 
Iteration: 1272928369, states[0] = -94.852525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1283835981, states[0] = -94.745067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1294707472, states[0] = -37.667069, states[40]= 0.001352
Saving checkpoint... 
Iteration: 1305857352, states[0] = -94.779604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1317324536, states[0] = -94.722752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1328575403, states[0] = 14.246751, states[40]= 0.005357
Saving checkpoint... 
Iteration: 1339735163, states[0] = -49.581291, states[40]= 0.000240
Saving checkpoint... 
Iteration: 1350869362, states[0] = -94.795856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1362249903, states[0] = -56.704232, states[40]= 0.000073
Saving checkpoint... 
Iteration: 1373391561, states[0] = -94.821159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1384676097, states[0] = -26.091212, states[40]= 0.004304
Saving checkpoint... 
Iteration: 1395997271, states[0] = -94.886905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1407244326, states[0] = -53.910887, states[40]= 0.000117
Saving checkpoint... 
Iteration: 1418611874, states[0] = 0.728973, states[40]= 0.005020
Saving checkpoint... 
Iteration: 1430449990, states[0] = -94.865723, states[40]= 0.000000
14:00:07 (8048): Can't acquire lockfile (32) - waiting 35s
14:00:45 (8048): Can't acquire lockfile (32) - exiting
14:00:45 (8048): Error: The process cannot access the file because it is being used by another process.

 (0x20)
Saving checkpoint... 
Iteration: 1441950954, states[0] = -94.866236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1444216258, states[0] = -41.266778, states[40]= 0.000835
Saving checkpoint... 
Iteration: 1453594684, states[0] = 7.374262, states[40]= 0.005471
Saving checkpoint... 
Iteration: 1465832124, states[0] = -94.737559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1477451861, states[0] = -94.866659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1489097875, states[0] = 6.183866, states[40]= 0.005438
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.763491
 - CaMKt in component CaMK (millimolar): 0.014947
 - cass in component intracellular_ions (millimolar): 0.000084
 - nai in component intracellular_ions (millimolar): 6.082458
 - nass in component intracellular_ions (millimolar): 6.082540
 - ki in component intracellular_ions (millimolar): 145.829800
 - kss in component intracellular_ions (millimolar): 145.829786
 - cansr in component intracellular_ions (millimolar): 1.585535
 - cajsr in component intracellular_ions (millimolar): 1.524174
 - cai in component intracellular_ions (millimolar): 0.000086
 - m in component INa (dimensionless): 0.003669
 - hf in component INa (dimensionless): 0.877579
 - hs in component INa (dimensionless): 0.877565
 - j in component INa (dimensionless): 0.877478
 - hsp in component INa (dimensionless): 0.721229
 - jp in component INa (dimensionless): 0.877391
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.647274
 - hLp in component INaL (dimensionless): 0.338039
 - a in component Ito (dimensionless): 0.000629
 - iF in component Ito (dimensionless): 0.999866
 - iS in component Ito (dimensionless): 0.491250
 - ap in component Ito (dimensionless): 0.000321
 - iFp in component Ito (dimensionless): 0.999866
 - iSp in component Ito (dimensionless): 0.546026
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.862617
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999262
 - jca in component ICaL (dimensionless): 0.999877
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002663
 - xrf in component IKr (dimensionless): 0.000004
 - xrs in component IKr (dimensionless): 0.503693
 - xs1 in component IKs (dimensionless): 0.350623
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997374
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
14:07:35 (22968): called boinc_finish(0)


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240622023434439622_ORdGradInc_k_23-TESZT_Block_Kr_70-conf_551.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240622023434439622_ORdGradInc_k_23-TESZT_Block_Kr_70-conf_551_1_r537273_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240622023434439622_ORdGradInc_k_23-TESZT_Block_Kr_70-conf_551_1_r537273_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 141.475340
     * GNaL_b in INaL: 0.003953
     * Gto_b in Ito: 0.083569
     * PCa_b in ICaL: 0.000082
     * GKr_b in IKr: 0.009923
     * GKs_b in IKs: 0.001676
     * GK1_b in IK1: 0.137721
     * Gncx_b in INaCa_i: 0.000935
     * Pnak_b in INaK: 75.455288
     * GKb_b in IKb: 0.004185
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.028685
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1489097875
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 6.183866 (After loading)
 - states[40]: 0.005438 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.763491
 - CaMKt in component CaMK (millimolar): 0.014947
 - cass in component intracellular_ions (millimolar): 0.000084
 - nai in component intracellular_ions (millimolar): 6.082458
 - nass in component intracellular_ions (millimolar): 6.082540
 - ki in component intracellular_ions (millimolar): 145.829800
 - kss in component intracellular_ions (millimolar): 145.829786
 - cansr in component intracellular_ions (millimolar): 1.585535
 - cajsr in component intracellular_ions (millimolar): 1.524174
 - cai in component intracellular_ions (millimolar): 0.000086
 - m in component INa (dimensionless): 0.003669
 - hf in component INa (dimensionless): 0.877579
 - hs in component INa (dimensionless): 0.877565
 - j in component INa (dimensionless): 0.877478
 - hsp in component INa (dimensionless): 0.721229
 - jp in component INa (dimensionless): 0.877391
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.647274
 - hLp in component INaL (dimensionless): 0.338039
 - a in component Ito (dimensionless): 0.000629
 - iF in component Ito (dimensionless): 0.999866
 - iS in component Ito (dimensionless): 0.491250
 - ap in component Ito (dimensionless): 0.000321
 - iFp in component Ito (dimensionless): 0.999866
 - iSp in component Ito (dimensionless): 0.546026
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.862617
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999262
 - jca in component ICaL (dimensionless): 0.999877
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002663
 - xrf in component IKr (dimensionless): 0.000004
 - xrs in component IKr (dimensionless): 0.503693
 - xs1 in component IKs (dimensionless): 0.350623
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997374
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
17:34:35 (12388): called boinc_finish(0)

</stderr_txt>
]]>


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