𝕏

Task 53969855

Name HuVeMOp_20240620173750286635_ORdGradInc_k_23-CLVPET_Block_K1_75-conf_180_0
Workunit 25626593
Created 20 Jun 2024, 16:00:12 UTC
Sent 21 Jun 2024, 1:38:42 UTC
Report deadline 24 Jun 2024, 4:31:30 UTC
Received 21 Jun 2024, 5:47:52 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 226319
Run time 3 hours 8 min 3 sec
CPU time 3 hours 1 min 20 sec
Validate state Valid
Credit 49.44
Device peak FLOPS 2.76 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.86 MB
Peak swap size 6.38 MB
Peak disk usage 0.06 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240620173750286635_ORdGradInc_k_23-CLVPET_Block_K1_75-conf_180.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240620173750286635_ORdGradInc_k_23-CLVPET_Block_K1_75-conf_180_0_r969665782_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240620173750286635_ORdGradInc_k_23-CLVPET_Block_K1_75-conf_180_0_r969665782_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 84.351464
     * GNaL_b in INaL: 0.005448
     * Gto_b in Ito: 0.070647
     * PCa_b in ICaL: 0.000083
     * GKr_b in IKr: 0.032459
     * GKs_b in IKs: 0.001936
     * GK1_b in IK1: 0.046672
     * Gncx_b in INaCa_i: 0.000921
     * Pnak_b in INaK: 58.594101
     * GKb_b in IKb: 0.003414
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.046815
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 10155960, states[0] = -67.533782, states[40]= 0.000002
Saving checkpoint... 
Iteration: 19946734, states[0] = -93.671102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 29497055, states[0] = -93.658721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 39143572, states[0] = -54.720311, states[40]= 0.000037
Saving checkpoint... 
Iteration: 48194502, states[0] = -85.686741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58008519, states[0] = 29.916716, states[40]= 0.076698
Saving checkpoint... 
Iteration: 67548344, states[0] = 19.473964, states[40]= 0.002014
Saving checkpoint... 
Iteration: 77066238, states[0] = 11.942479, states[40]= 0.003421
Saving checkpoint... 
Iteration: 86835797, states[0] = -93.310771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 96582815, states[0] = 3.209153, states[40]= 0.004318
Saving checkpoint... 
Iteration: 106365286, states[0] = -93.402060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 116114858, states[0] = -25.923379, states[40]= 0.001053
Saving checkpoint... 
Iteration: 125912973, states[0] = -93.501099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 135746070, states[0] = -92.556906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 145621183, states[0] = -32.287278, states[40]= 0.000757
Saving checkpoint... 
Iteration: 155371273, states[0] = -93.412383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 164783989, states[0] = -93.023705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 174641762, states[0] = -52.548205, states[40]= 0.000054
Saving checkpoint... 
Iteration: 183713404, states[0] = -90.338549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 193532761, states[0] = 25.351319, states[40]= 0.001206
Saving checkpoint... 
Iteration: 203375124, states[0] = -93.420307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 213193251, states[0] = -84.947412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 222630091, states[0] = -41.181866, states[40]= 0.000286
Saving checkpoint... 
Iteration: 232442806, states[0] = -93.537419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 242195812, states[0] = -85.902212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 252088230, states[0] = -0.336957, states[40]= 0.004224
Saving checkpoint... 
Iteration: 261779628, states[0] = -92.987985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 271734387, states[0] = -92.181237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 281697720, states[0] = -86.562078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 291690833, states[0] = -83.970098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 301701717, states[0] = -87.799787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311672583, states[0] = -74.883001, states[40]= 0.000001
Saving checkpoint... 
Iteration: 321099907, states[0] = -10.402936, states[40]= 0.002476
Saving checkpoint... 
Iteration: 330978758, states[0] = -93.570753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 340844457, states[0] = -93.328655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 350798457, states[0] = -93.117266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 360754879, states[0] = -92.717325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 370661152, states[0] = -67.855874, states[40]= 0.000003
Saving checkpoint... 
Iteration: 380546127, states[0] = 20.395162, states[40]= 0.001880
Saving checkpoint... 
Iteration: 390443829, states[0] = -93.537539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 400346503, states[0] = -93.335396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 410156295, states[0] = -64.483748, states[40]= 0.000007
Saving checkpoint... 
Iteration: 420061943, states[0] = 13.921485, states[40]= 0.003089
Saving checkpoint... 
Iteration: 429665952, states[0] = -70.944093, states[40]= 0.000002
Saving checkpoint... 
Iteration: 439590785, states[0] = -2.237025, states[40]= 0.004032
Saving checkpoint... 
Iteration: 449500271, states[0] = -60.017417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 458894278, states[0] = -93.461088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 468883005, states[0] = -93.437035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 478678241, states[0] = -77.980513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 488660586, states[0] = -67.475772, states[40]= 0.000004
Saving checkpoint... 
Iteration: 498600879, states[0] = -11.383875, states[40]= 0.002278
Saving checkpoint... 
Iteration: 508599988, states[0] = -10.483118, states[40]= 0.002459
Saving checkpoint... 
Iteration: 518529504, states[0] = 26.432468, states[40]= 0.001128
Saving checkpoint... 
Iteration: 528469008, states[0] = -93.561940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 538371048, states[0] = -93.407746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 548269270, states[0] = -92.894271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 558130397, states[0] = -41.481143, states[40]= 0.000275
Saving checkpoint... 
Iteration: 567932502, states[0] = -93.522833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 577746801, states[0] = -92.566243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 587706935, states[0] = -89.117302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 597136752, states[0] = -47.766176, states[40]= 0.000114
Saving checkpoint... 
Iteration: 607067655, states[0] = 11.338530, states[40]= 0.003542
Saving checkpoint... 
Iteration: 617023635, states[0] = 28.120308, states[40]= 0.001327
Saving checkpoint... 
Iteration: 626984862, states[0] = -93.573815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 636914223, states[0] = -93.496028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 646880645, states[0] = -93.430783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 656771886, states[0] = -92.919007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 666754608, states[0] = -92.711518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 676753867, states[0] = -92.699609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 686692687, states[0] = -84.718580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 696281862, states[0] = -93.003238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 706239952, states[0] = -92.384489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 716184553, states[0] = -81.153799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 725844162, states[0] = -93.325788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 735589005, states[0] = -0.895211, states[40]= 0.004177
Saving checkpoint... 
Iteration: 745536938, states[0] = 23.873410, states[40]= 0.001371
Saving checkpoint... 
Iteration: 755501358, states[0] = 44.425165, states[40]= 0.358013
Saving checkpoint... 
Iteration: 765135311, states[0] = -46.354783, states[40]= 0.000140
Saving checkpoint... 
Iteration: 775045927, states[0] = 20.473569, states[40]= 0.001867
Saving checkpoint... 
Iteration: 784992064, states[0] = -93.577933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 795011062, states[0] = 29.757118, states[40]= 0.032501
Saving checkpoint... 
Iteration: 804975987, states[0] = -93.566375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 814878526, states[0] = -93.425009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 824915727, states[0] = -93.497539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 834851754, states[0] = -93.350687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 844821368, states[0] = -93.234371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 854722269, states[0] = -91.401711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 864206303, states[0] = -88.972452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 874054463, states[0] = 17.076802, states[40]= 0.002485
Saving checkpoint... 
Iteration: 883992411, states[0] = -93.577695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 893501211, states[0] = 44.172521, states[40]= 0.298190
Saving checkpoint... 
Iteration: 903127477, states[0] = -38.563777, states[40]= 0.000397
Saving checkpoint... 
Iteration: 912762813, states[0] = -92.822333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 922265707, states[0] = -92.855268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 931452761, states[0] = -93.544747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 941398149, states[0] = -93.466404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 951292731, states[0] = -93.078657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 961104399, states[0] = -15.026154, states[40]= 0.001662
Saving checkpoint... 
Iteration: 970636753, states[0] = -47.765226, states[40]= 0.000114
Saving checkpoint... 
Iteration: 980533786, states[0] = 24.999572, states[40]= 0.001242
Saving checkpoint... 
Iteration: 990418410, states[0] = -93.500930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 999820027, states[0] = -93.227512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1009690530, states[0] = -83.837103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1019429816, states[0] = -93.517166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1029315857, states[0] = -93.207703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1039224761, states[0] = -91.610786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1049135217, states[0] = -46.260900, states[40]= 0.000142
Saving checkpoint... 
Iteration: 1059106786, states[0] = -17.528363, states[40]= 0.001377
Saving checkpoint... 
Iteration: 1069065298, states[0] = 12.427417, states[40]= 0.003360
Saving checkpoint... 
Iteration: 1079011320, states[0] = 29.751511, states[40]= 0.029813
Saving checkpoint... 
Iteration: 1088919762, states[0] = -93.502521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1098854384, states[0] = -93.357755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1108727551, states[0] = -91.810115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1118658555, states[0] = -66.082283, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1128615364, states[0] = -26.376132, states[40]= 0.001041
Saving checkpoint... 
Iteration: 1138060783, states[0] = 14.426845, states[40]= 0.002995
Saving checkpoint... 
Iteration: 1148029768, states[0] = 26.349019, states[40]= 0.001132
Saving checkpoint... 
Iteration: 1157926203, states[0] = -93.511558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167857928, states[0] = -93.368251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1177793209, states[0] = -93.080663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1187728047, states[0] = -91.841674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1197710653, states[0] = -89.862908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1207647798, states[0] = -57.855710, states[40]= 0.000022
Saving checkpoint... 
Iteration: 1217567827, states[0] = 11.258871, states[40]= 0.003556
Saving checkpoint... 
Iteration: 1227449022, states[0] = -93.539412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1237054478, states[0] = 17.071235, states[40]= 0.002486
Saving checkpoint... 
Iteration: 1246985276, states[0] = -93.571219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1256880382, states[0] = -93.427309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1266864977, states[0] = -93.388078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1276388187, states[0] = -93.444657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1286280056, states[0] = -92.986277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1296103909, states[0] = -14.512164, states[40]= 0.001735
Saving checkpoint... 
Iteration: 1305792120, states[0] = -93.072975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1315717459, states[0] = -90.888488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1325625667, states[0] = -36.751583, states[40]= 0.000490
Saving checkpoint... 
Iteration: 1335577447, states[0] = 6.380848, states[40]= 0.004165
Saving checkpoint... 
Iteration: 1345492922, states[0] = -93.575873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1355451301, states[0] = -93.541246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1365436509, states[0] = -93.524223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1375391342, states[0] = -93.450827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1385333613, states[0] = -93.283546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1395250435, states[0] = -92.636081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1405203874, states[0] = -88.376116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1414539923, states[0] = 22.770141, states[40]= 0.001516
Saving checkpoint... 
Iteration: 1424408771, states[0] = -93.483339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1434379231, states[0] = -93.423774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1444272722, states[0] = -92.922930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1454170589, states[0] = -73.727418, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1464039639, states[0] = 22.876548, states[40]= 0.001501
Saving checkpoint... 
Iteration: 1473972843, states[0] = -93.560740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1483860565, states[0] = -93.374543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493638138, states[0] = -49.104234, states[40]= 0.000093
Saving checkpoint... 
Iteration: 1503202969, states[0] = 5.607310, states[40]= 0.008051
Saving checkpoint... 
Iteration: 1513055026, states[0] = 12.231082, states[40]= 0.003973
Saving checkpoint... 
Iteration: 1522875808, states[0] = -84.296169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1532788062, states[0] = 23.067528, states[40]= 0.000744
Saving checkpoint... 
Iteration: 1542602566, states[0] = -92.862492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1551963153, states[0] = -93.151279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1561816623, states[0] = -92.754106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1571652418, states[0] = -92.681269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1581508076, states[0] = 28.375962, states[40]= 0.087354
Saving checkpoint... 
Iteration: 1591278716, states[0] = -92.188865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1601110508, states[0] = -7.897294, states[40]= 0.002819
Saving checkpoint... 
Iteration: 1610996123, states[0] = -91.997926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1620786546, states[0] = -91.719461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1630370168, states[0] = -91.322438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1640190769, states[0] = -67.624216, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1649871341, states[0] = -91.337271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1659665243, states[0] = -91.299905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1669459088, states[0] = -91.273020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1678843893, states[0] = -91.306991, states[40]= 0.000000
Total time: 3360000.000000
State Variables:
 - v in component membrane (millivolt): -91.093681
 - CaMKt in component CaMK (millimolar): 0.001062
 - cass in component intracellular_ions (millimolar): 0.000084
 - nai in component intracellular_ions (millimolar): 6.248457
 - nass in component intracellular_ions (millimolar): 6.248536
 - ki in component intracellular_ions (millimolar): 145.653628
 - kss in component intracellular_ions (millimolar): 145.653616
 - cansr in component intracellular_ions (millimolar): 1.519655
 - cajsr in component intracellular_ions (millimolar): 1.519808
 - cai in component intracellular_ions (millimolar): 0.000087
 - m in component INa (dimensionless): 0.005313
 - hf in component INa (dimensionless): 0.796846
 - hs in component INa (dimensionless): 0.796848
 - j in component INa (dimensionless): 0.796858
 - hsp in component INa (dimensionless): 0.586133
 - jp in component INa (dimensionless): 0.796864
 - mL in component INaL (dimensionless): 0.000102
 - hL in component INaL (dimensionless): 0.618282
 - hLp in component INaL (dimensionless): 0.414662
 - a in component Ito (dimensionless): 0.000806
 - iF in component Ito (dimensionless): 0.999746
 - iS in component Ito (dimensionless): 0.996801
 - ap in component Ito (dimensionless): 0.000411
 - iFp in component Ito (dimensionless): 0.999746
 - iSp in component Ito (dimensionless): 0.998672
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998805
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002671
 - xrf in component IKr (dimensionless): 0.000005
 - xrs in component IKr (dimensionless): 0.003900
 - xs1 in component IKs (dimensionless): 0.023686
 - xs2 in component IKs (dimensionless): 0.000135
 - xk1 in component IK1 (dimensionless): 0.998173
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
21:46:46 (8236): called boinc_finish(0)

</stderr_txt>
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