𝕏

Task 53773412

Name HuVeMOp_20240619161237489060_ORdGradInc_k_22-Pueyo_APDR-conf_256_0
Workunit 25530146
Created 19 Jun 2024, 14:13:20 UTC
Sent 19 Jun 2024, 15:28:38 UTC
Report deadline 23 Jun 2024, 1:04:38 UTC
Received 19 Jun 2024, 23:09:18 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 213754
Run time 3 hours 11 min 44 sec
CPU time 3 hours 7 min 23 sec
Validate state Valid
Credit 58.82
Device peak FLOPS 3.72 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.57 MB
Peak swap size 6.22 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240619161237489060_ORdGradInc_k_22-Pueyo_APDR-conf_256.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240619161237489060_ORdGradInc_k_22-Pueyo_APDR-conf_256_0_r1677729349_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240619161237489060_ORdGradInc_k_22-Pueyo_APDR-conf_256_0_r1677729349_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 64.966087
     * GNaL_b in INaL: 0.016336
     * Gto_b in Ito: 0.070723
     * PCa_b in ICaL: 0.000084
     * GKr_b in IKr: 0.029500
     * GKs_b in IKs: 0.002176
     * GK1_b in IK1: 0.197723
     * Gncx_b in INaCa_i: 0.000922
     * Pnak_b in INaK: 61.914569
     * GKb_b in IKb: 0.003205
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.062685
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12128408, states[0] = -15.697865, states[40]= 0.001348
Saving checkpoint... 
Iteration: 24282725, states[0] = -94.891279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35732625, states[0] = -94.835745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 47784989, states[0] = -94.890977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59727156, states[0] = -94.827914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 71769098, states[0] = -94.876752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 83903934, states[0] = -94.948486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 96092407, states[0] = 5.490672, states[40]= 0.004513
Saving checkpoint... 
Iteration: 108180887, states[0] = -62.326871, states[40]= 0.000007
Saving checkpoint... 
Iteration: 120174337, states[0] = -54.242007, states[40]= 0.000026
Saving checkpoint... 
Iteration: 132182813, states[0] = -64.980152, states[40]= 0.000004
Saving checkpoint... 
Iteration: 144401685, states[0] = -94.948054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 156293189, states[0] = -94.897818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 168169926, states[0] = -49.316488, states[40]= 0.000057
Saving checkpoint... 
Iteration: 180213797, states[0] = -94.801116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 192306268, states[0] = -94.907164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 204383580, states[0] = -94.942948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 216370112, states[0] = -94.938523, states[40]= 0.000000
Saving checkpoint... 
Iteration: 228100037, states[0] = 1.892617, states[40]= 0.004273
Saving checkpoint... 
Iteration: 240083552, states[0] = 9.277252, states[40]= 0.004629
Saving checkpoint... 
Iteration: 251969966, states[0] = -94.960800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 263896825, states[0] = -94.946706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 275941733, states[0] = -94.956486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 288003741, states[0] = 32.675538, states[40]= 0.193308
Saving checkpoint... 
Iteration: 300135887, states[0] = -21.447435, states[40]= 0.001249
Saving checkpoint... 
Iteration: 312179108, states[0] = -60.032336, states[40]= 0.000010
Saving checkpoint... 
Iteration: 324014483, states[0] = 28.040216, states[40]= 0.015274
Saving checkpoint... 
Iteration: 336075979, states[0] = 12.265260, states[40]= 0.004653
Saving checkpoint... 
Iteration: 348238346, states[0] = -94.842482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 360336931, states[0] = -94.924612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 372414435, states[0] = -94.950961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 384465979, states[0] = -94.960142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396513636, states[0] = 28.011337, states[40]= 0.018160
Saving checkpoint... 
Iteration: 408569557, states[0] = 14.634459, states[40]= 0.004627
Saving checkpoint... 
Iteration: 420588918, states[0] = 7.020690, states[40]= 0.004573
Saving checkpoint... 
Iteration: 432602793, states[0] = 0.497692, states[40]= 0.004130
Saving checkpoint... 
Iteration: 444523724, states[0] = 27.509740, states[40]= 0.005552
Saving checkpoint... 
Iteration: 456555695, states[0] = 19.285304, states[40]= 0.004431
Saving checkpoint... 
Iteration: 468548320, states[0] = 21.548503, states[40]= 0.004300
Saving checkpoint... 
Iteration: 480587564, states[0] = 7.601754, states[40]= 0.004591
Saving checkpoint... 
Iteration: 492623272, states[0] = -12.309514, states[40]= 0.001811
Saving checkpoint... 
Iteration: 504676684, states[0] = -57.030802, states[40]= 0.000017
Saving checkpoint... 
Iteration: 516732977, states[0] = -94.835498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 528809223, states[0] = -94.908808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 540835638, states[0] = -94.923809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 553003938, states[0] = 32.146761, states[40]= 0.189030
Saving checkpoint... 
Iteration: 565075084, states[0] = 12.604216, states[40]= 0.004652
Saving checkpoint... 
Iteration: 576727958, states[0] = -94.828872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 588809392, states[0] = -94.908861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 600713633, states[0] = -94.799921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 612580283, states[0] = 10.594069, states[40]= 0.004646
Saving checkpoint... 
Iteration: 624637808, states[0] = -22.817696, states[40]= 0.001244
Saving checkpoint... 
Iteration: 636720011, states[0] = -94.817443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 648808463, states[0] = -94.908201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 660858584, states[0] = -94.933837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 672999946, states[0] = -94.963841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685119532, states[0] = -9.651582, states[40]= 0.002283
Saving checkpoint... 
Iteration: 697037444, states[0] = 24.623630, states[40]= 0.004303
Saving checkpoint... 
Iteration: 708999735, states[0] = -94.963787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 721132630, states[0] = -19.111193, states[40]= 0.001254
Saving checkpoint... 
Iteration: 732819890, states[0] = -94.915172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 744684340, states[0] = -67.218906, states[40]= 0.000003
Saving checkpoint... 
Iteration: 756632724, states[0] = -19.178949, states[40]= 0.001253
Saving checkpoint... 
Iteration: 768622536, states[0] = -11.779764, states[40]= 0.001896
Saving checkpoint... 
Iteration: 780707524, states[0] = -94.699869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 792918115, states[0] = -94.951390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 804978868, states[0] = -94.961415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 816961878, states[0] = -94.959166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 829041113, states[0] = 23.630675, states[40]= 0.004257
Saving checkpoint... 
Iteration: 841079431, states[0] = 10.930483, states[40]= 0.004649
Saving checkpoint... 
Iteration: 853162573, states[0] = -41.983654, states[40]= 0.000171
Saving checkpoint... 
Iteration: 865277290, states[0] = -94.883993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 877408135, states[0] = -94.949020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 889485840, states[0] = -94.962152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 901327268, states[0] = -94.919148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 913400708, states[0] = -94.947130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 925501723, states[0] = 40.283840, states[40]= 0.138561
Saving checkpoint... 
Iteration: 937629224, states[0] = -16.641440, states[40]= 0.001339
Saving checkpoint... 
Iteration: 949680895, states[0] = -62.355619, states[40]= 0.000007
Saving checkpoint... 
Iteration: 961891114, states[0] = -94.944478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 973921589, states[0] = -94.951970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 985958032, states[0] = -94.958449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 998076855, states[0] = 11.930825, states[40]= 0.004653
Saving checkpoint... 
Iteration: 1010184540, states[0] = -67.520811, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1022334223, states[0] = -94.922655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1034381507, states[0] = -94.941542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1046370785, states[0] = -94.937992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1058486876, states[0] = -94.962112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1070589382, states[0] = 6.819807, states[40]= 0.004567
Saving checkpoint... 
Iteration: 1082527520, states[0] = 26.895421, states[40]= 0.004887
Saving checkpoint... 
Iteration: 1094485153, states[0] = -94.961884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1106618627, states[0] = -9.023803, states[40]= 0.002408
Saving checkpoint... 
Iteration: 1118849880, states[0] = -94.929838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1131029984, states[0] = 26.407303, states[40]= 0.004645
Saving checkpoint... 
Iteration: 1143187893, states[0] = -73.029274, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1155233302, states[0] = -94.835321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167357211, states[0] = -94.932823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1179485433, states[0] = -94.961837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1191564012, states[0] = 16.566077, states[40]= 0.004570
Saving checkpoint... 
Iteration: 1203618715, states[0] = -9.084481, states[40]= 0.002396
Saving checkpoint... 
Iteration: 1215758898, states[0] = -94.865594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1227947057, states[0] = -94.956505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1240020491, states[0] = 27.870190, states[40]= 0.006771
Saving checkpoint... 
Iteration: 1252123978, states[0] = -12.819539, states[40]= 0.001734
Saving checkpoint... 
Iteration: 1264186662, states[0] = -70.901409, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1276157064, states[0] = -37.214231, states[40]= 0.000337
Saving checkpoint... 
Iteration: 1287891620, states[0] = -94.944319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1300061606, states[0] = 17.373271, states[40]= 0.004535
Saving checkpoint... 
Iteration: 1311451665, states[0] = -94.957172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1323352406, states[0] = -94.930717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1335589905, states[0] = 6.592095, states[40]= 0.004559
Saving checkpoint... 
Iteration: 1347776643, states[0] = -94.882961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1359983617, states[0] = -94.961462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1372128919, states[0] = -16.419039, states[40]= 0.001352
Saving checkpoint... 
Iteration: 1383716119, states[0] = -94.808575, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1395916179, states[0] = -94.950403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1407821894, states[0] = -94.915698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1419768902, states[0] = -94.875626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1431985414, states[0] = -94.961601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1444195648, states[0] = -88.286831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1455871928, states[0] = -94.938007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1467912689, states[0] = -94.949545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1479913085, states[0] = -94.949625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1490922227, states[0] = -94.951624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1502346136, states[0] = -95.102712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1513878943, states[0] = 3.634420, states[40]= 0.005085
Saving checkpoint... 
Iteration: 1526022864, states[0] = -95.087073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1538023299, states[0] = -95.093107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1549643589, states[0] = -50.319170, states[40]= 0.000055
Saving checkpoint... 
Iteration: 1561555612, states[0] = 14.020239, states[40]= 0.005481
Saving checkpoint... 
Iteration: 1573483935, states[0] = -95.162427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1585582352, states[0] = 0.765050, states[40]= 0.004901
Saving checkpoint... 
Iteration: 1597808222, states[0] = 28.131444, states[40]= 0.069478
Saving checkpoint... 
Iteration: 1609910634, states[0] = -20.669445, states[40]= 0.001244
Saving checkpoint... 
Iteration: 1621694743, states[0] = -95.060337, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1633825611, states[0] = 25.199256, states[40]= 0.006159
Saving checkpoint... 
Iteration: 1645371948, states[0] = -94.118017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1657177382, states[0] = -95.162018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1669298338, states[0] = -10.559325, states[40]= 0.002489
Saving checkpoint... 
Iteration: 1681452570, states[0] = -95.140891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1693614439, states[0] = -23.873554, states[40]= 0.001148
Saving checkpoint... 
Iteration: 1705572594, states[0] = 5.974783, states[40]= 0.005384
Saving checkpoint... 
Iteration: 1717529508, states[0] = 24.009959, states[40]= 0.005720
Saving checkpoint... 
Iteration: 1729615755, states[0] = -24.955110, states[40]= 0.001108
Saving checkpoint... 
Iteration: 1741682775, states[0] = -95.025003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1753669835, states[0] = -93.091064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1765252983, states[0] = 14.992997, states[40]= 0.005466
Saving checkpoint... 
Iteration: 1777328932, states[0] = -36.056218, states[40]= 0.000408
Saving checkpoint... 
Iteration: 1789033735, states[0] = -40.520964, states[40]= 0.000226
Saving checkpoint... 
Iteration: 1800770806, states[0] = -94.919200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1812242436, states[0] = -94.867609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1824100912, states[0] = 0.422230, states[40]= 0.004191
Saving checkpoint... 
Iteration: 1835910139, states[0] = -94.963808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1847596364, states[0] = 3.207025, states[40]= 0.004406
Saving checkpoint... 
Iteration: 1859421616, states[0] = -94.958836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1870870239, states[0] = -94.942484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1882702879, states[0] = -94.309803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1894743597, states[0] = -94.850100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1906861253, states[0] = -94.935522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1918967905, states[0] = -94.960211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1931006389, states[0] = 28.636638, states[40]= 0.113072
Saving checkpoint... 
Iteration: 1943093816, states[0] = 4.820186, states[40]= 0.004482
Saving checkpoint... 
Iteration: 1955231297, states[0] = -94.832299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1967106691, states[0] = -1.605377, states[40]= 0.003851
Saving checkpoint... 
Iteration: 1978837666, states[0] = -94.923566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1990927238, states[0] = -94.952217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2002675566, states[0] = -55.708776, states[40]= 0.000021
Saving checkpoint... 
Iteration: 2014666053, states[0] = -45.315977, states[40]= 0.000105
Saving checkpoint... 
Iteration: 2026257736, states[0] = -94.863510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2038222344, states[0] = -94.819661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2049863967, states[0] = -94.934497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2061429562, states[0] = -94.952466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2073060993, states[0] = 17.575869, states[40]= 0.004525
Saving checkpoint... 
Iteration: 2084616679, states[0] = -7.699555, states[40]= 0.002682
Saving checkpoint... 
Iteration: 2096652893, states[0] = -33.894576, states[40]= 0.000525
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.838267
 - CaMKt in component CaMK (millimolar): 0.008285
 - cass in component intracellular_ions (millimolar): 0.000076
 - nai in component intracellular_ions (millimolar): 6.974648
 - nass in component intracellular_ions (millimolar): 6.974706
 - ki in component intracellular_ions (millimolar): 144.989075
 - kss in component intracellular_ions (millimolar): 144.989057
 - cansr in component intracellular_ions (millimolar): 1.361721
 - cajsr in component intracellular_ions (millimolar): 1.318085
 - cai in component intracellular_ions (millimolar): 0.000077
 - m in component INa (dimensionless): 0.003642
 - hf in component INa (dimensionless): 0.878893
 - hs in component INa (dimensionless): 0.878889
 - j in component INa (dimensionless): 0.878864
 - hsp in component INa (dimensionless): 0.723750
 - jp in component INa (dimensionless): 0.878847
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.698045
 - hLp in component INaL (dimensionless): 0.423381
 - a in component Ito (dimensionless): 0.000626
 - iF in component Ito (dimensionless): 0.999868
 - iS in component Ito (dimensionless): 0.579520
 - ap in component Ito (dimensionless): 0.000319
 - iFp in component Ito (dimensionless): 0.999868
 - iSp in component Ito (dimensionless): 0.647075
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.890535
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999670
 - jca in component ICaL (dimensionless): 0.999943
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001810
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.394079
 - xs1 in component IKs (dimensionless): 0.316239
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997354
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
13:57:36 (10716): called boinc_finish(0)

</stderr_txt>
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