𝕏

Task 53118471

Name HuVeMOp_20240614164641641120_ORdGradInc_k_21-Schmidt_1000-conf_181_0
Workunit 25222045
Created 14 Jun 2024, 15:06:07 UTC
Sent 15 Jun 2024, 3:18:48 UTC
Report deadline 18 Jun 2024, 3:18:48 UTC
Received 15 Jun 2024, 11:04:36 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 217041
Run time 2 hours 14 min 8 sec
CPU time 2 hours 11 min 48 sec
Validate state Valid
Credit 41.48
Device peak FLOPS 3.79 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.74 MB
Peak swap size 4.10 GB
Peak disk usage 0.33 MB

Stderr output

<core_client_version>7.24.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240614164641641120_ORdGradInc_k_21-Schmidt_1000-conf_181.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240614164641641120_ORdGradInc_k_21-Schmidt_1000-conf_181_0_r237511078_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240614164641641120_ORdGradInc_k_21-Schmidt_1000-conf_181_0_r237511078_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 93.859234
     * GNaL_b in INaL: 0.004247
     * Gto_b in Ito: 0.042455
     * PCa_b in ICaL: 0.000082
     * GKr_b in IKr: 0.034514
     * GKs_b in IKs: 0.001822
     * GK1_b in IK1: 0.204777
     * Gncx_b in INaCa_i: 0.000956
     * Pnak_b in INaK: 60.527583
     * GKb_b in IKb: 0.003418
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.056281
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 11707102, states[0] = -84.323689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 23456272, states[0] = -84.701152, states[40]= 0.000001
Saving checkpoint... 
Iteration: 35211872, states[0] = -84.283790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 46925062, states[0] = -84.683413, states[40]= 0.000001
Saving checkpoint... 
Iteration: 58658509, states[0] = -83.061155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 70398686, states[0] = -84.667390, states[40]= 0.000001
Saving checkpoint... 
Iteration: 81825872, states[0] = -84.596989, states[40]= 0.000001
Saving checkpoint... 
Iteration: 93526388, states[0] = 30.537868, states[40]= 0.000184
Saving checkpoint... 
Iteration: 105282813, states[0] = -84.520286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 117013911, states[0] = 34.242877, states[40]= 0.013900
Saving checkpoint... 
Iteration: 128768414, states[0] = -84.485095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 140467242, states[0] = -84.697081, states[40]= 0.000001
Saving checkpoint... 
Iteration: 152221581, states[0] = -84.323675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 163846913, states[0] = -84.621419, states[40]= 0.000001
Saving checkpoint... 
Iteration: 175622197, states[0] = -38.856360, states[40]= 0.000095
Saving checkpoint... 
Iteration: 187324627, states[0] = -84.593359, states[40]= 0.000001
Saving checkpoint... 
Iteration: 199060397, states[0] = 14.541365, states[40]= 0.000114
Saving checkpoint... 
Iteration: 210725789, states[0] = -84.341030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 222462355, states[0] = -84.694461, states[40]= 0.000001
Saving checkpoint... 
Iteration: 234233390, states[0] = -84.371453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 245965793, states[0] = -84.695298, states[40]= 0.000001
Saving checkpoint... 
Iteration: 257280089, states[0] = -84.512019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 267448039, states[0] = -84.688857, states[40]= 0.000001
Saving checkpoint... 
Iteration: 276855092, states[0] = -84.628701, states[40]= 0.000001
Saving checkpoint... 
Iteration: 286252897, states[0] = -84.438760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 295734737, states[0] = -84.375911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 307351286, states[0] = -84.624426, states[40]= 0.000001
Saving checkpoint... 
Iteration: 319069651, states[0] = 9.722363, states[40]= 0.000206
Saving checkpoint... 
Iteration: 330792067, states[0] = -84.536863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 342503074, states[0] = 36.788245, states[40]= 0.613515
Saving checkpoint... 
Iteration: 354250979, states[0] = -84.431934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 366000104, states[0] = -71.914231, states[40]= 0.000001
Saving checkpoint... 
Iteration: 377749294, states[0] = -84.426249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 389462686, states[0] = -84.692663, states[40]= 0.000001
Saving checkpoint... 
Iteration: 401168969, states[0] = -83.995215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 412896657, states[0] = -84.661185, states[40]= 0.000001
Saving checkpoint... 
Iteration: 424646404, states[0] = -69.890624, states[40]= 0.000001
Saving checkpoint... 
Iteration: 436401824, states[0] = -84.664207, states[40]= 0.000001
Saving checkpoint... 
Iteration: 448112285, states[0] = -27.535864, states[40]= 0.000211
Saving checkpoint... 
Iteration: 459845112, states[0] = -84.615970, states[40]= 0.000001
Saving checkpoint... 
Iteration: 471581861, states[0] = 2.702162, states[40]= 0.000405
Saving checkpoint... 
Iteration: 483317614, states[0] = -84.579731, states[40]= 0.000001
Saving checkpoint... 
Iteration: 494953106, states[0] = -84.688162, states[40]= 0.000001
Saving checkpoint... 
Iteration: 506676684, states[0] = -84.072264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 518435103, states[0] = -84.680705, states[40]= 0.000001
Saving checkpoint... 
Iteration: 530187175, states[0] = -84.139192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 541925711, states[0] = -84.676114, states[40]= 0.000001
Saving checkpoint... 
Iteration: 553653994, states[0] = -80.462703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 565469368, states[0] = -84.692782, states[40]= 0.000001
Saving checkpoint... 
Iteration: 577185515, states[0] = -84.128555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 588893162, states[0] = -84.656858, states[40]= 0.000001
Saving checkpoint... 
Iteration: 600556056, states[0] = 16.727545, states[40]= 0.000084
Saving checkpoint... 
Iteration: 612247341, states[0] = -84.417134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 623931509, states[0] = -84.677904, states[40]= 0.000001
Saving checkpoint... 
Iteration: 635650372, states[0] = -76.108664, states[40]= 0.000001
Saving checkpoint... 
Iteration: 647373887, states[0] = -84.641716, states[40]= 0.000001
Saving checkpoint... 
Iteration: 659052525, states[0] = 18.475923, states[40]= 0.000066
Saving checkpoint... 
Iteration: 670728057, states[0] = -84.345098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 682437026, states[0] = -84.679679, states[40]= 0.000001
Saving checkpoint... 
Iteration: 694129949, states[0] = -47.752516, states[40]= 0.000033
Saving checkpoint... 
Iteration: 705836119, states[0] = -84.602552, states[40]= 0.000001
Saving checkpoint... 
Iteration: 717546506, states[0] = 21.407047, states[40]= 0.000043
Saving checkpoint... 
Iteration: 729248555, states[0] = -84.419781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 740924491, states[0] = -84.673263, states[40]= 0.000001
Saving checkpoint... 
Iteration: 752379617, states[0] = -84.645135, states[40]= 0.000001
Saving checkpoint... 
Iteration: 764024356, states[0] = 31.341613, states[40]= 0.000363
Saving checkpoint... 
Iteration: 775731284, states[0] = -84.356906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 787463149, states[0] = -84.688303, states[40]= 0.000001
Saving checkpoint... 
Iteration: 799157123, states[0] = -82.504827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 810864894, states[0] = -84.632033, states[40]= 0.000001
Saving checkpoint... 
Iteration: 822547693, states[0] = 20.834221, states[40]= 0.000046
Saving checkpoint... 
Iteration: 834211069, states[0] = -84.266692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 845938287, states[0] = -84.678363, states[40]= 0.000001
Saving checkpoint... 
Iteration: 857608027, states[0] = -22.595900, states[40]= 0.000236
Saving checkpoint... 
Iteration: 869292885, states[0] = -84.532325, states[40]= 0.000001
Saving checkpoint... 
Iteration: 880944142, states[0] = -84.680374, states[40]= 0.000001
Saving checkpoint... 
Iteration: 892648533, states[0] = -73.279291, states[40]= 0.000001
Saving checkpoint... 
Iteration: 904376129, states[0] = -84.640631, states[40]= 0.000001
Saving checkpoint... 
Iteration: 916095890, states[0] = -8.600341, states[40]= 0.000488
Saving checkpoint... 
Iteration: 927813363, states[0] = -84.568068, states[40]= 0.000001
Saving checkpoint... 
Iteration: 939125777, states[0] = -42.916514, states[40]= 0.000060
Saving checkpoint... 
Iteration: 950827268, states[0] = -84.588257, states[40]= 0.000001
Saving checkpoint... 
Iteration: 962498938, states[0] = -84.696005, states[40]= 0.000001
Saving checkpoint... 
Iteration: 974202107, states[0] = -84.219073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 985903901, states[0] = -84.659239, states[40]= 0.000001
Saving checkpoint... 
Iteration: 997033978, states[0] = 27.286450, states[40]= 0.000029
Saving checkpoint... 
Iteration: 1008510151, states[0] = 34.451199, states[40]= 0.052156
Saving checkpoint... 
Iteration: 1020207258, states[0] = -84.245447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031857879, states[0] = -84.622879, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1043567032, states[0] = 11.119037, states[40]= 0.000175
Saving checkpoint... 
Iteration: 1055264199, states[0] = -84.462949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1066986623, states[0] = -84.691905, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1078662089, states[0] = -83.670771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1090338155, states[0] = -84.600662, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1102003083, states[0] = 36.772017, states[40]= 0.611595
Saving checkpoint... 
Iteration: 1113715189, states[0] = -84.283250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1125369575, states[0] = -84.632620, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1136893010, states[0] = -84.650529, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1148366830, states[0] = -84.629940, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1160062157, states[0] = 13.649792, states[40]= 0.000127
Saving checkpoint... 
Iteration: 1171636134, states[0] = -55.222071, states[40]= 0.000012
Saving checkpoint... 
Iteration: 1183214082, states[0] = -84.277195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1194787106, states[0] = -84.516728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1205720323, states[0] = -84.305733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1217001634, states[0] = 37.242623, states[40]= 0.891796
Saving checkpoint... 
Iteration: 1228739476, states[0] = -84.382726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1240468303, states[0] = -84.684804, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1252204258, states[0] = -84.227216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1263914978, states[0] = -84.662430, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1275627004, states[0] = -44.317288, states[40]= 0.000050
Saving checkpoint... 
Iteration: 1287313053, states[0] = -84.563467, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1299040820, states[0] = 24.123014, states[40]= 0.000029
Saving checkpoint... 
Iteration: 1310730744, states[0] = -84.348549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1322539823, states[0] = 24.592334, states[40]= 0.000027
Saving checkpoint... 
Iteration: 1334260774, states[0] = -84.450155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1346005855, states[0] = 34.635125, states[40]= 0.234992
Saving checkpoint... 
Iteration: 1357736847, states[0] = -84.371564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1369495581, states[0] = -84.690637, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1381199141, states[0] = -84.198222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1392960898, states[0] = -84.680695, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1404668909, states[0] = -83.981867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1416351798, states[0] = -84.612330, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1427367005, states[0] = -84.626921, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1439110860, states[0] = -25.871192, states[40]= 0.000220
Saving checkpoint... 
Iteration: 1450921003, states[0] = -84.663465, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1462730774, states[0] = -84.346904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1474527019, states[0] = 30.295590, states[40]= 0.000150
Saving checkpoint... 
Iteration: 1486334705, states[0] = -84.591885, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1498098205, states[0] = -11.095869, states[40]= 0.000433
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -84.566024
 - CaMKt in component CaMK (millimolar): 0.015573
 - cass in component intracellular_ions (millimolar): 0.000089
 - nai in component intracellular_ions (millimolar): 6.819002
 - nass in component intracellular_ions (millimolar): 6.819113
 - ki in component intracellular_ions (millimolar): 144.989826
 - kss in component intracellular_ions (millimolar): 144.989805
 - cansr in component intracellular_ions (millimolar): 1.738719
 - cajsr in component intracellular_ions (millimolar): 1.684848
 - cai in component intracellular_ions (millimolar): 0.000091
 - m in component INa (dimensionless): 0.010242
 - hf in component INa (dimensionless): 0.573009
 - hs in component INa (dimensionless): 0.572986
 - j in component INa (dimensionless): 0.572861
 - hsp in component INa (dimensionless): 0.326314
 - jp in component INa (dimensionless): 0.572773
 - mL in component INaL (dimensionless): 0.000353
 - hL in component INaL (dimensionless): 0.392184
 - hLp in component INaL (dimensionless): 0.190720
 - a in component Ito (dimensionless): 0.001251
 - iF in component Ito (dimensionless): 0.999204
 - iS in component Ito (dimensionless): 0.561149
 - ap in component Ito (dimensionless): 0.000638
 - iFp in component Ito (dimensionless): 0.999204
 - iSp in component Ito (dimensionless): 0.603508
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.911824
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999818
 - jca in component ICaL (dimensionless): 0.999974
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003246
 - xrf in component IKr (dimensionless): 0.000014
 - xrs in component IKr (dimensionless): 0.500160
 - xs1 in component IKs (dimensionless): 0.272353
 - xs2 in component IKs (dimensionless): 0.000279
 - xk1 in component IK1 (dimensionless): 0.996783
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
04:20:26 (83550): called boinc_finish(0)

</stderr_txt>
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