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Posts by Jesús Carro

41) Message boards : Number crunching : Invalid task (Message 2068)
Posted 14 Apr 2023 by Profile Jesús Carro
Post:
Hi Dayle,
We have observed an small increment in the non valid results. We are analazying what is happening. Neverless, the percentage of non valid is still very small. More than checkpointing problems, it is related usually with problems opening or saving the file (which depends on the operative system).

I will keep you updated.

Best,
Jesús.
42) Message boards : Number crunching : Checksum error (Message 2060)
Posted 13 Apr 2023 by Profile Jesús Carro
Post:
Hi Crystal,
Thanks for the warning. It should already be fixed.

Best,
Jesús.
43) Message boards : News : Status of the project // Estado del proyecto (Message 2056)
Posted 11 Apr 2023 by Profile Jesús Carro
Post:
Dear volunteers,
We update you on the status of the project and how the simulations are going. In recent weeks the search algorithm has been improving the model very little. This indicates us that the optimization is close to be finished. Once this is complete we will pass to the validation phase which we will be done outside of DENIS (DENIS is not yet prepare for the required simulations).

The improvement obtained is very considerable (you can see the graph with the evolution of the error below and we hope that the validation results turn out well). It can be improved, but not all the error can be removed with the optimization (it requires other type of improvements in the model).

On the other hand, looking at the results, last week we started a new optimization by changing an aspect of it. In the initial search, if one of the markers was in the experimentally observed range, we did not allow the algorithm to search where that marker was outside of the experimental range (criterion of keeping at least those markers that were already in the experimental range). In the new search we are allowing it in the hope that even if some marker goes out, the overall behavior will improve. In this case, the uncertainty about the result is higher, but as you can see in the graph below, after the first iterations of the algorithm, the results are quite promising.

Sincerely,
Jesus.





========================================


Estimados voluntarios:
Os actualizamos el estado del proyecto y cómo van las simulaciones. En las últimas semanas el algoritmo de búsqueda ha ido mejorando muy poco el modelo. Esto nos indica que está a punto de terminarse la optimización. Una vez que esto se complete, pasaremos a una fase de validación de la simulación que haremos fuera de DENIS (DENIS no está preparado para ello).

La mejoría obtenida es muy considerable y esperamos que los resultados de la validación salgan bien (podéis ver la gráfica con la evolución del error debajo). Todavía hay margen de mejora, pero no todo el error se puede eliminar en la optimización (requiere otro tipo de mejoras en el modelo).

Por otro lado, viendo los resultados, la semana pasada comenzamos una nueva optimización cambiando un aspecto de la misma. En la búsqueda inicial, si uno de los marcadores estaba en el rango observado experimentalmente, no permitíamos al algoritmo buscar donde ese marcador saliera del rango experimental (criterio de mantener en rango experimental al menos los que ya estaban). En la nueva búsqueda estamos permitiéndolo con la esperanza de que aunque algún marcador salga fuera, el comportamiento global mejore. En este caso la incertidumbre sobre el resultado es algo mayor, pero como podéis ver en la gráfica de debajo, tras las primeras iteraciones del algoritmo, los resultados son bastante prometedores.

Atentamente,
Jesús.

44) Message boards : Number crunching : Stat's Export (Message 2046)
Posted 16 Mar 2023 by Profile Jesús Carro
Post:
Once per day is the recommended frequency in the BOINC documentation. We could increase it, but I don't see the need and it would generate more workload and space problems (all previously exported ones are saved)

Best,
Jesús.
45) Questions and Answers : Macintosh : Computation error on Mac OS 10.6.7 (Message 2044)
Posted 14 Mar 2023 by Profile Jesús Carro
Post:
Yes, we want to add the app for 32bits in RaspberryPi. We will review this soon.
46) Questions and Answers : Macintosh : Computation error on Mac OS 10.6.7 (Message 2042)
Posted 13 Mar 2023 by Profile Jesús Carro
Post:
Hi!
In this new relaunch of the project we had stopped compiling for 32 bits because there were already too many versions and we assumed that there were no more hosts (or only a few). We are automating the build process, if I see that it is easy, we will add it.

Best,
Jesús.
47) Message boards : Number crunching : Invalid task (Message 2041)
Posted 13 Mar 2023 by Profile Jesús Carro
Post:
No, don't worry. I will check the code and later I will analyze the results of your tasks.

Thank you.
48) Message boards : Number crunching : Invalid task (Message 2038)
Posted 10 Mar 2023 by Profile Jesús Carro
Post:
Hi David. It is in our side. The difference is really small, with this information I will review what is happening to try to improve. We have very few invalid simulations, to find them help us a lot.

Thank you a lot

Best,
Jesús.
49) Questions and Answers : Macintosh : Computation error on Mac OS 10.6.7 (Message 2033)
Posted 9 Mar 2023 by Profile Jesús Carro
Post:
Hi!
Indeed, it seems that it may be an OS version issue. In principle our program should compile for 10.5 or later, but I have to review the options on Mac because something is not going quite right. I put it on the top of my to-do list to see if I can review it next week.

Best,
Jesús.
50) Message boards : News : Update of the results of the last 15 days // Actualización de los resultados de estos últimos 15 días (Message 2029)
Posted 8 Mar 2023 by Profile Jesús Carro
Post:
Dear volunteers,
Allow me a brief message to update you on how the results are going after 15 more days of simulation.
5 iterations of the algorithm have already been completed. Of the 100 markers that we are using, 89 have already been achieved in the normal range (initially only 77 were). On the other hand, the distance between the average experimental behavior and the model has been reduced by 56.84%.

Several parameters of the algorithm indicate that there is still room for improvement.

We will keep you informed.

All the best,
Jesus.

===================================================

Estimados voluntarios:
Permitidme un breve mensaje para actualizaros cómo van los resultados después de 15 días más de simulación.
Se han completado ya 5 iteraciones del algoritmo. De los 100 marcadores que estamos utilizando, ya se ha conseguido que 89 estén en rango normal (inicialmente solo lo estaban 77). Por otro lado, la distancia entre el comportamiento medio experimental y el modelo se ha reducido un 56.84%.

Varios parámetros del algoritmo nos indican que sigue habiendo margen de mejora.

Os mantendremos informados.

Un saludo,
Jesús.
51) Message boards : News : DENIS merchandising on the BOINC web store // Merchandising de DENIS en la tienda web de BOINC (Message 2027)
Posted 23 Feb 2023 by Profile Jesús Carro
Post:
Dear volunteers,
The Science Commons Initiative has created a store to sell merchandising from BOINC projects to help fund the development of BOINC and the projects as well.

We have given them permission so you can find products with the DENIS logo. 50% of the profits on these products will go to develop BOINC and the other 50% will be donated to support DENIS.

You can see them at https://www.redbubble.com/es/shop/ap/138889661

However, if you have any questions about the products or anything related to the store, you can contact them. We are only responsible for having given permission to use the logo.

All the best,
Jesus.

=================================================

Estimados voluntarios:
La Science Commons Initiative ha creado una tienda para vender merchandising de proyectos BOINC para ayudar a financiar el desarrollo de BOINC y también a los proyectos.

Les hemos dado permiso así que podréis encontrar productos con el logo de DENIS. El 50% de los beneficios en estos productos irán para desarrollar BOINC y el otro 50% lo donarán para apoyar a DENIS.

Podéis verlos en https://www.redbubble.com/es/shop/ap/138889661

No obstante, cualquier duda con los productos o cualquier cosa relacionada con la tienda, podéis poneros en contacto con ellos. Nosotros solo somos responsables de haber dado permiso para utilizar el logo.

Un saludo,
Jesús.
52) Questions and Answers : Web site : No stats for MacOs computers (Message 2026)
Posted 23 Feb 2023 by Profile Jesús Carro
Post:
I don't know what is happening. There are Mac Computers runing tasks: https://denis.usj.es/denisathome/cpu_list.php. And they compute this project: https://denis.usj.es/denisathome/projects.php#NHuVe
53) Message boards : News : Results of the first iteration of the algorithm // Resultados de la primera iteración del algoritmo (Message 2024)
Posted 22 Feb 2023 by Profile Jesús Carro
Post:
Dear volunteers,
We have good news! After processing the results of the first iteration, we have found a combination of model parameters that improves the behavior of the model compared to the initial one. In the original version, of the 100 markers that we are using, 77 were in the experimental range: now there are 80. On the other hand, the distance between the model and the average experimental behavior has been reduced by almost 30%.

The values of several of the parameters that have been modified are in the limit of the area that we had used in the first iteration, so the search area has been expanded (this is parameterized in the algorithm).

The tasks of the second iteration are already being sent. We will continue to inform you of how the results are going.

Thank you very much to all!

Best,
Jesús.

===============================================================

Estimados voluntarios:
¡Tenemos buenas noticias! Después de procesar los resultados de la primera iteración hemos encontrado una combinación de parámetros del modelo que mejora el comportamiento respecto del inicial que teníamos. En la versión original, de los 100 marcadores que estamos utilizando, 77 estaban en rango experimental: ahora ya están 80. Por otro lado, la distancia entre el modelo y el comportamiento medio experimental se ha reducido casi en un 30%.

Los valores de varios de los parámetros que se han modificado estan en el límite de la zona que habíamos utilizado en la primera iteracción, así que se ha ampliado la zona de búsqueda (esto está parametrizado en el algoritmos).

Ya están enviándose las tareas de la segunda iteracción. Os seguiremos informando de cómo van los resultados.

¡Muchas gracias a todos!

Un saludo,
Jesús.
54) Message boards : News : Results of the last simulations and next steps // Resultados de las últimas simulaciones y siguientes pasos (Message 2022)
Posted 20 Feb 2023 by Profile Jesús Carro
Post:
Hi TLD,
In the project we are trying to improve a model of human ventricular cells. We know now that one of the characteristics will not be included in this version, so we will need you for the next improvement of the model. This, in addition to the other subprojects that we have not yet started. In short, we will continue needing you.

Best,
Jesús
55) Message boards : News : New simulations // Nuevas simulaciones (Message 2021)
Posted 20 Feb 2023 by Profile Jesús Carro
Post:
No, but we should prepare some material to explain it better. I add it to my to-do list.

Thanks.
56) Message boards : News : Results of the last simulations and next steps // Resultados de las últimas simulaciones y siguientes pasos (Message 2016)
Posted 17 Feb 2023 by Profile Jesús Carro
Post:
Dear volunteers,

I have both good and bad news to share with you regarding our recent progress. First, the good news: thanks to the results you've sent in, we have been able to identify the problem with the marker and gain a better understanding of what was happening. Additionally, it turns out that we won't need to increase the number of simulations per iteration, which is good news (for us).

However, there is also some bad news to report. We've discovered that the behavior of the model with this marker is highly non-linear, which means that it cannot be effectively addressed within the framework of our current approximation. While this could be disappointing, we can assume this limitation in the model, as it was measured experimentally under unrealistic conditions.

Once we've fine-tuned the model, we will determine whether this non-linear behavior persists, or whether it disappears with the changes we've made. If the issue does persist, we'll need to address it in the next phase of our work, which means there may be more work to come for some of you. We'll keep you updated on our progress.

We're grateful for your continued efforts and support.

Best regards,
Jesus.

===========================================

Estimados voluntarios:
Tengo noticias buenas y malas que compartir con vosotros sobre nuestro progreso reciente. Primero, las buenas noticias: gracias a los resultados que habéis enviado, hemos logrado identificar el problema con el marcador y obtener una mejor comprensión de lo que estaba sucediendo. Además, resulta que no necesitaremos aumentar el número de simulaciones por iteración, lo cual es una buena noticia (para nosotros).

Sin embargo, también hay malas noticias que reportar. Hemos descubierto que el comportamiento del modelo con este marcador es altamente no lineal, lo que significa que no puede ser abordado de manera efectiva dentro del marco de nuestra aproximación actual. Si bien esto puede ser decepcionante, podemos asumir esta limitación en el modelo, ya que se midió experimentalmente en condiciones poco realistas.

Una vez que hayamos ajustado el modelo, determinaremos si este comportamiento no lineal persiste o si desaparece con los cambios que hemos realizado. Si el problema persiste, tendremos que abordarlo en la siguiente fase de nuestro trabajo, lo que significa que puede haber más trabajo por hacer para algunos de ustedes. Os mantendremos informados sobre nuestro progreso

Muchas gracias por vuestro esfuerzo y apoyo continuo.

Atentamente,
Jesús.
57) Message boards : News : New simulations // Nuevas simulaciones (Message 2015)
Posted 15 Feb 2023 by Profile Jesús Carro
Post:
Now we are out of work again, what's next in the project?
Will this project ever turn into a massive output of tasks like some of the other projects on BOINC or will this be an on and off type project as you complete each section?


Yes, in the future we should have a constant flow of tasks, but first we need to finish fine-tuning the algorithm and how we work with the models. These first ones are a test with a model that we hope to extend later, but for now we are launching part by part to analyze. We don't want to put it in automatic mode and then have to throw a lot away.
58) Message boards : News : New simulations // Nuevas simulaciones (Message 2014)
Posted 15 Feb 2023 by Profile Jesús Carro
Post:
How are things looking so far with the current models?


We are analyzing the results, but it is not clear yet what it is happening with one marker. Our hypotheses so far have not been fruitful.
59) Message boards : News : New simulations // Nuevas simulaciones (Message 2008)
Posted 8 Feb 2023 by Profile Jesús Carro
Post:
We are adding them carefully to not saturate the server. So far it is being able to handle more than we expected... 😀
60) Message boards : Number crunching : I sent a PM to an admin here (Message 2003)
Posted 2 Feb 2023 by Profile Jesús Carro
Post:
Sorry, busy days. I've answered you a few minutes ago. No problem from my side, but asGreg_BE said, the project isn't stable enough.

Best,
Jesús.


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