Beta blockers have long been widely prescribed for patients with heart issues, but two new studies this week question the benefit of the therapies in certain patients with strong heart function.

One study, published Tuesday in Heart, looked at people who experienced a heart attack but didn’t develop heart failure or dysfunction in their heart’s pumping. Researchers found that long-term beta blocker use wasn’t associated with improved cardiovascular outcomes in this group.

The other study, published Wednesday in JACC: Heart Failure, focused on people with heart failure who had mildly reduced and normal ejection fraction, which is a measure of a heart’s squeezing function. The authors found that beta blockers were linked to a greater risk of hospitalization in patients with higher squeezing power.