Violeta Monasterio

Telecommunications Engineer, Master in Biomedical Engineering and PhD in Biomedical Engineering at the University of Zaragoza.

Her research interests are focused on the application of computational techniques for cellular electrical modeling and for the processing of biomedical signals. She has participated in several national and international research projects. In 2009 she conducted a research stay at the Laboratory for Computational Physiology at the Massachusetts Institute of Technology (MIT), and during 2011 and 2012 she worked as a researcher at the Institute of Biomedical Engineering at the University of Oxford.

Publications

Journal Articles

Monasterio, V.; Castro, J.; Carro, J.

DENIS: Solving cardiac electrophysiological simulations with volunteer computing Journal Article

In: PLoS One, vol. 13, no. 10, pp. e0205568, 2018, ISSN: 1932-6203.

Ramírez, J.; Orini, M.; Mincholé, A.; Monasterio, V.; Cygankiewicz, I.; Bayés de Luna, A.; Martínez, J. P.; Laguna, P.; Pueyo, E.

Sudden cardiac death and pump failure death prediction in chronic heart failure by combining ECG and clinical markers in an integrated risk model Journal Article

In: PLoS One, vol. 12, no. 10, pp. e0186152 1-15 , 2017.

Carro, J.; Rodríguez Matas, J. F.; Monasterio, V.; Pueyo, E.

Limitations in electrophysiological model development and validation caused by differences between simulations and experimental protocols Journal Article

In: Progress in Biophysics and Molecular Biology, vol. 129, pp. 53-64, 2017, ISSN: 0079-6107.

Martín-Yebra, A.; Monasterio, V.; Cygankiewicz, I.; Bayés de Luna, A.; Caiani, E. G.; Laguna, P.; Martínez, J. P.

Post-ventricular premature contraction phase correction improves the predictive value of average T-wave alternans in ambulatory ECG recordings Journal Article

In: IEEE Transactions Biomedical Engineering, vol. 65, no. 3, pp. 635–644, 2017.

Ramírez, J.; Orini, M.; Mincholé, A.; Monasterio, V.; Cygankiewicz, I.; Bayés de Luna, A.; Martínez, J. P.; Pueyo, E.; Laguna, P.

T-Wave Morphology Restitution Predicts Sudden Cardiac Death in Patients With Chronic Heart Failure Journal Article

In: Journal of the American Heart Association, vol. 6, no. 5, 2017, ISSN: 2047-9980.

Abstract | Links | BibTeX

@article{Ramirez2017,

title = {T-Wave Morphology Restitution Predicts Sudden Cardiac Death in Patients With Chronic Heart Failure},

author = {Ramírez, J. and Orini, M. and Mincholé, A. and Monasterio, V. and Cygankiewicz, I. and Bayés de Luna, A. and Martínez, J.P. and Pueyo, E. and Laguna, P.},

url = {http://jaha.ahajournals.org/content/6/5/e005310},

doi = {10.1161/JAHA.116.005310},

issn = {2047-9980},

year  = {2017},

date = {2017-01-01},

journal = {Journal of the American Heart Association},

volume = {6},

number = {5},

publisher = {American Heart Association, Inc.},

abstract = {Background Patients with chronic heart failure are at high risk of sudden cardiac death (SCD). Increased dispersion of repolarization restitution has been associated with SCD, and we hypothesize that this should be reflected in the morphology of the T-wave and its variations with heart rate. The aim of this study is to propose an electrocardiogram (ECG)-based index characterizing T-wave morphology restitution (TMR), and to assess its association with SCD risk in a population of chronic heart failure patients.Methods and Results Holter ECGs from 651 ambulatory patients with chronic heart failure from the MUSIC (MUerte S'ubita en Insuficiencia Cardiaca) study were available for the analysis. TMR was quantified by measuring the morphological variation of the T-wave per RR increment using time-warping metrics, and its predictive power was compared to that of clinical variables such as the left ventricular ejection fraction and other ECG-derived indices, such as T-wave alternans and heart rate variability. TMR was significantly higher in SCD victims than in the rest of patients (median 0.046 versus 0.039, P<0.001). When TMR was dichotomized at TMR=0.040, the SCD rate was significantly higher in the TMR>=0.040 group (P<0.001). Cox analysis revealed that TMR>=0.040 was strongly associated with SCD, with a hazard ratio of 3.27 (P<0.001), independently of clinical and ECG-derived variables. No association was found between TMR and pump failure death.Conclusions This study shows that TMR is specifically associated with SCD in a population of chronic heart failure patients, and it is a better predictor than clinical and ECG-derived variables.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

Martin-Yebra, A.; Caiani, E.; Monasterio, V.; Pellegrini, A.; Laguna, P.; Martinez, J. P.

Evaluation of T-wave alternans activity under stress conditions after 5 days and 21 days of sedentary head-down bed-rest Journal Article

In: Physiological measurement, vol. 36, pp. 2041–2055, 2015.

Ramírez, J.; Monasterio, V.; Mincholé, A.; Llamedo, M.; Lenis, G.; Cygankiewicz, I.; Bayés De Luna, A.; Malik, M.; Martínez, J. P.; Laguna, P.; Pueyo, E.

Automatic SVM classification of sudden cardiac death and pump failure death from autonomic and repolarization ECG markers Journal Article

In: Journal of Electrocardiology, vol. 48, no. 4, pp. 551-557, 2015.

Roebuck, A.; Monasterio, V.; Gederi, E.; Osipov, M.; Behar, J.; Malhotra, A.; Penzel, T.; Clifford, G. D.

A review of signals used in sleep analysis Journal Article

In: Physiological Measurement, vol. 35, no. 1, pp. R1-R57, 2014.

Orini, M.; Hanson, B.; Monasterio, V.; Martínez, J. P.; Hayward, M.; Taggart, P.; Lambiase, P.

Comparative evaluation of methodologies for T-wave alternans mapping in electrograms Journal Article

In: IEEE Transactions on Biomedical Engineering, vol. 61, no. 2, pp. 308-316, 2014.

Monasterio, V.; Martínez, J. P.; Laguna, P.; McNitt, S.; Polonsky, S.; Moss, A. J.; Haigney, M.; Zareba, W.; Couderc, J. P.

Prognostic value of average T-wave alternans and QT variability for cardiac events in MADIT-II patients Journal Article

In: Journal of Electrocardiology, vol. 46, no. 6, pp. 480-486, 2013.

Demidova, M. M.; Martín Yebra, A.; Martínez, J. P.; Monasterio, V.; Koul, S.; Van Der Pals, J.; Romero, D.; Laguna, P.; Erlinge, D.; Platonov, P. G.

T wave alternans in experimental myocardial infarction: Time course and predictive value for the assessment of myocardial damage Journal Article

In: Journal of Electrocardiology, vol. 46, no. 3, pp. 263-269, 2013.

Monasterio, V.; Laguna, P.; Cygankiewicz, I.; Vázquez, R.; Bayés-Genís, A.; Bayés De Luna, A.; Martínez, J. P.

Average T-wave alternans activity in ambulatory ECG records predicts sudden cardiac death in patients with chronic heart failure Journal Article

In: Heart Rhythm, vol. 9, no. 3, pp. 383-389, 2012.

Monasterio, V.; Burgess, F.; Clifford, G. D.

Robust classification of neonatal apnoea-related desaturations Journal Article

In: Physiological Measurement, vol. 33, no. 9, pp. 1503-1516, 2012.

Nemati, S.; Abdala, O.; Monasterio, V.; Yim-Yeh, S.; Malhotra, A.; Clifford, G. D.

A nonparametric surrogate-based test of significance for T-wave alternans detection Journal Article

In: IEEE Transactions on Biomedical Engineering, vol. 58, no. 5, pp. 1356-1364, 2011.

Monasterio, V.; Clifford, G. D.; Laguna, P.; Martínez, J. P.

A multilead scheme based on periodic component analysis for T-Wave alternans analysis in the ECG Journal Article

In: Annals of Biomedical Engineering, vol. 38, no. 8, pp. 2532-2541, 2010.

Monasterio, V.; Laguna, P.; Martínez, J. P.

Multilead analysis of T-wave alternans in the ecg using principal component analysis Journal Article

In: IEEE Transactions on Biomedical Engineering, vol. 56, no. 7, pp. 1880-1890, 2009.

Inproceedings

Monasterio, V.; Pueyo, E.; Rodríguez-Matas, J. F.; Carro, J.

Influence of the Stimulation Current on the Differences Between Cell and Tissue Electrophysiological Simulations Inproceedings

In: 2019 Computing in Cardiology (CinC), 2019, ISBN: 978-1-7281-6936-1.

Abstract | Links | BibTeX

Monasterio, V.; Pueyo, E.; Rodríguez-Matas, J. F.; Carro, J.

Influencia de la corriente de estimulación en las diferencias entre simulaciones electrofisiológicas de célula y tejido. Inproceedings

In: XXXVI Congreso Anual de la Sociedad Española de Ingeniería Biomédica, Ciudad Real, pp. 125 - 128, 2018, ISBN: 978-84-09-06253-9.

Martín-Yebra, A.; Monasterio, V.; Laguna, P.; Martínez, J. P.; Caiani, E. G.

Evaluation of Changes in T-wave Alternans Induced by 60-days of Immobilization by Head-Down Bed-Rest Inproceedings

In: Proceedings of the XLIV International Conference on Computing in Cardiology. Rennes, France, pp. 1-4, 2017.

García-Escolano, A.; Mora, M. T.; Monasterio, V.; Rodríguez, J. F.; Ferrero, J. M.

Estudio mediante modelado y simulación del efecto de la isquemia miocárdica aguda en las fibras de Purkinje de corazón humano Inproceedings

In: Proceedings XXXIV Congreso Anual de la Sociedad Española de Ingeniería Biomédica, pp. 471-474, 2016, ISBN: 978-84-9048-531-6.

Castro, J.; Monasterio, V.; Carro, J.

Volunteer Computing Approach for the Collaborative Simulation of Electrophysiological Models Inproceedings

In: 2016 IEEE 25th International Conference on Enabling Technologies: Infrastructure for Collaborative Enterprises (WETICE), pp. 118-123, 2016.

Marcén, A. C.; Carro, J.; Monasterio, V.

Wearable Monitoring for the Detection of Nocturnal Agitation in Dementia Inproceedings

In: Proceedings of the 6th International Joint Conference on Pervasive and Embedded Computing and Communication Systems, pp. 63-69, 2016, ISBN: 978-989-758-195-3.

Monasterio, V.; Carro, J.; Rodríguez Matas, J. F.; Pueyo, E.

The Role of Purkinje Automaticity as an Arrhythmia Mechanism in Hyperkalaemia Inproceedings

In: Computing in Cardiology, pp. 873-876, 2015.

Martín Yebra, A.; Caiani, E. G.; Laguna, P.; Monasterio, V.; Martínez, J. P.

Circadian Modulation on T-wave Alternans Activity in Chronic Heart Failure Patients Inproceedings

In: Computing in Cardiology, pp. 845-848, 2015.

Monasterio, V.; Carro, J.; Pueyo, E.

Repolarization alternans in human ventricular hyperkalaemic tissue: dependence on current stimulation Inproceedings

In: XXXII Congreso Anual de la Sociedad Española de Ingeniería Biomédica, Barcelona, pp. 1-4, 2014, ISBN: 9788461724468.

Martín Yebra, A.; Caiani, E. G.; Monasterio, V.; Pellegrini, A.; Laguna, P.; Martínez, J. P.

T-wave alternans and autonomic nervous system activity during orthostatic stress after 5 days of head-down bed-rest Inproceedings

In: 2014 8th Conference of the European Study Group on Cardiovascular Oscillations, ESGCO 2014, pp. 115-116, 2014.

Monasterio, V.; Martinez, J. P.; McNitt, S.; Laguna, P.; Moss, A. J.; Zareba, W.; Couderc, J. P.

T-wave alternans predicts ICD discharge in MADIT II patients with elevated resting heart rate Inproceedings

In: Computing in Cardiology, pp. 603-606, 2013.

Martin Yebra, A.; Monasterio, V.; Pellegrini, A.; Laguna, P.; Caiani, E. G.; Martinez, J. P.

Effect of simulated microgravity by head-down bed rest on T wave alternans Inproceedings

In: Computing in Cardiology, pp. 377-380, 2012.

Daly, J.; Monasterio, V.; Clifford, G. D.

A neonatal apnoea monitor for resource-constrained environments Inproceedings

In: Computing in Cardiology, pp. 321-324, 2012.

Martínez, J. P.; Martín Yebra, A.; Monasterio, V.; Demidova, M. M.; Platonov, P. G.; Laguna, P.

Time course and spatial distribution of T wave alternans induced by coronary artery occlusion in pigs Inproceedings

In: Computing in Cardiology, pp. 669-672, 2011.

Monasterio, V.; Laguna, P.; Cygankiewicz, I.; Martínez, J. P.

Average T-wave alternans activity in ambulatory ECGs Inproceedings

In: Computing in Cardiology, pp. 621-624, 2011.

Monasterio, V.; Clifford, G. D.; Martínez, J. P.

Comparison of source separation techniques for multilead T-wave alternans detection in the ECG Inproceedings

In: 2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10, pp. 5367-5370, 2010.

Monasterio, V.; Martínez, J. P.

Comparison of two eigenvalue decomposition techniques to detect T wave alternans in the ECG Inproceedings

In: IFMBE Proceedings, pp. 631-634, 2009.

Monasterio, V.; Laguna, P.; Martínez, J. P.

Multilead estimation of T-wave alternans in the ECG using principal component analysis Inproceedings

In: European Signal Processing Conference, 2008.

Monasterio, V.; Martínez, J. P.

Multilead T-Wave Alternans quantification based on spatial filtering and the Laplacian likelihood ratio method Inproceedings

In: Computers in Cardiology, pp. 601-604, 2008.

Monasterio, V.; Martínez, J. P.

A multilead approach to T-wave alternans detection combining principal component analysis and the laplacian ikelihood ratio method Inproceedings

In: Computers in Cardiology, pp. 5-8, 2007.

Gil, E.; Monasterio, V.; Laguna, P.; Vergara, J. M.

Pulse photopletismography amplitude decrease detector for sleep apnea evaluation in children Inproceedings

In: Annual International Conference of the IEEE Engineering in Medicine and Biology, pp. 2743-2746, 2005.

PhD Theses

Monasterio, V.

Multilead analysis of T-wave alternans in the electrocardiogram PhD Thesis

University of Zaragoza, 2011.

Masters Theses

Monasterio, V.

Análisis multiderivacional de alternancias de onda T en el ECG Masters Thesis

University of Zaragoza, University of Zaragoza, SPAIN, 2008.