2019
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PhD Theses
|
Carro, J New methodologies for the development and validation of electrophysiological models Universtity of Zaragoza, 2019. Links | BibTeX @phdthesis{Carro2019,
title = {New methodologies for the development and validation of electrophysiological models },
author = {Carro, J.},
url = {http://diec.unizar.es/~laguna/personal/publicaciones/ThesisJCarro.pdf},
year = {2019},
date = {2019-01-23},
school = {Universtity of Zaragoza},
keywords = {},
pubstate = {published},
tppubtype = {phdthesis}
}
|
2018
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Journal Articles
|
Monasterio, V; Castro, J; Carro, J DENIS: Solving cardiac electrophysiological simulations with volunteer computing PLoS One, 13 (10), pp. e0205568, 2018, ISSN: 1932-6203. Links | BibTeX @article{Monasterio2018,
title = {DENIS: Solving cardiac electrophysiological simulations with volunteer computing},
author = {Monasterio, V. and Castro, J. and Carro, J.},
editor = {Alexander V. Panfilov, Universiteit Gent, BELGIUM},
url = {https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0205568
https://denis.usj.es/wp-content/uploads/2018/10/journal.pone_.0205568.pdf},
doi = {10.1371/journal.pone.0205568},
issn = {1932-6203},
year = {2018},
date = {2018-10-16},
journal = {PLoS One},
volume = {13},
number = {10},
pages = {e0205568},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
Carro, J; Pueyo, E; Rodríguez Matas, J F A response surface optimization approach to adjust ionic current conductances of cardiac electrophysiological models. Application to the study of potassium level changes PLoS One, 13 (10), pp. e0204411, 2018, ISSN: 1932-6203. Abstract | Links | BibTeX @article{carro2018,
title = {A response surface optimization approach to adjust ionic current conductances of cardiac electrophysiological models. Application to the study of potassium level changes},
author = {Carro, J. and Pueyo, E. and Rodríguez Matas, J.F.},
url = {https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0204411},
doi = {10.1371/journal.pone.0204411},
issn = {1932-6203},
year = {2018},
date = {2018-10-03},
journal = {PLoS One},
volume = {13},
number = {10},
pages = {e0204411},
abstract = {Cardiac electrophysiological computational models are often developed from previously published models. The new models may incorporate additional features to adapt the model to a different species or may upgrade a specific ionic formulation based on newly available experimental data. A relevant challenge in the development of a new model is the estimation of certain ionic current conductances that cannot be reliably identified from experiments. A common strategy to estimate those conductances is by means of constrained non-linear least-squares optimization. In this work, a novel methodology is proposed for estimation of ionic current conductances of cardiac electrophysiological models by using a response surface approximation-based constrained optimization with trust region management. Polynomial response surfaces of a number of electrophysiological markers were built using statistical sampling methods. These markers included action potential duration (APD), triangulation, diastolic and systolic intracellular calcium concentration, and time constants of APD rate adaptation. The proposed methodology was applied to update the Carro et al. human ventricular action potential model after incorporation of intracellular potassium ([K+]i) dynamics. While the Carro et al. model was well suited for investigation of arrhythmogenesis, it did not allow simulation of [K+]i changes. With the methodology proposed in this study, the updated Carro et al. human ventricular model could be used to simulate [K+]i changes in response to varying extracellular potassium ([K+]o) levels. Additionally, it rendered values of evaluated electrophysiological markers within physiologically plausible ranges. The optimal values of ionic current conductances in the updated model were found in a notably shorter time than with previously proposed methodologies. As a conclusion, the response surface optimization-based approach proposed in this study allows estimating ionic current conductances of cardiac electrophysiological computational models while guaranteeing replication of key electrophysiological features and with an important reduction in computational cost with respect to previously published approaches. The updated Carro et al. model developed in this study is thus suitable for the investigation of arrhythmic risk-related conditions, including those involving large changes in potassium concentration.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Cardiac electrophysiological computational models are often developed from previously published models. The new models may incorporate additional features to adapt the model to a different species or may upgrade a specific ionic formulation based on newly available experimental data. A relevant challenge in the development of a new model is the estimation of certain ionic current conductances that cannot be reliably identified from experiments. A common strategy to estimate those conductances is by means of constrained non-linear least-squares optimization. In this work, a novel methodology is proposed for estimation of ionic current conductances of cardiac electrophysiological models by using a response surface approximation-based constrained optimization with trust region management. Polynomial response surfaces of a number of electrophysiological markers were built using statistical sampling methods. These markers included action potential duration (APD), triangulation, diastolic and systolic intracellular calcium concentration, and time constants of APD rate adaptation. The proposed methodology was applied to update the Carro et al. human ventricular action potential model after incorporation of intracellular potassium ([K+]i) dynamics. While the Carro et al. model was well suited for investigation of arrhythmogenesis, it did not allow simulation of [K+]i changes. With the methodology proposed in this study, the updated Carro et al. human ventricular model could be used to simulate [K+]i changes in response to varying extracellular potassium ([K+]o) levels. Additionally, it rendered values of evaluated electrophysiological markers within physiologically plausible ranges. The optimal values of ionic current conductances in the updated model were found in a notably shorter time than with previously proposed methodologies. As a conclusion, the response surface optimization-based approach proposed in this study allows estimating ionic current conductances of cardiac electrophysiological computational models while guaranteeing replication of key electrophysiological features and with an important reduction in computational cost with respect to previously published approaches. The updated Carro et al. model developed in this study is thus suitable for the investigation of arrhythmic risk-related conditions, including those involving large changes in potassium concentration. |
2017
|
Journal Articles
|
Ramírez, J; Orini, M; Mincholé, A; Monasterio, V; Cygankiewicz, I; Bayés de Luna, A; Martínez, J P; Laguna, P; Pueyo, E Sudden cardiac death and pump failure death prediction in chronic heart failure by combining ECG and clinical markers in an integrated risk model PLoS One, 12 (10), pp. e0186152 1-15 , 2017. Links | BibTeX @article{Ramirez2017b,
title = {Sudden cardiac death and pump failure death prediction in chronic heart failure by combining ECG and clinical markers in an integrated risk model},
author = {Ramírez, J. and Orini, M. and Mincholé, A. and Monasterio, V. and Cygankiewicz, I. and Bayés de Luna, A. and Martínez, J.P. and Laguna, P. and Pueyo, E. },
url = {https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0186152},
doi = {doi:10.1371/journal.pone.0186152},
year = {2017},
date = {2017-10-11},
journal = {PLoS One},
volume = {12},
number = {10},
pages = {e0186152 1-15 },
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
Carro, J; Rodríguez Matas, J F; Monasterio, V; Pueyo, E Limitations in electrophysiological model development and validation caused by differences between simulations and experimental protocols Progress in Biophysics and Molecular Biology, 129 , pp. 53-64, 2017, ISSN: 0079-6107. Links | BibTeX @article{Carro2017a,
title = {Limitations in electrophysiological model development and validation caused by differences between simulations and experimental protocols},
author = {Carro, J. and Rodríguez Matas, J.F. and Monasterio, V. and Pueyo, E.},
url = {http://www.sciencedirect.com/science/article/pii/S007961071630013X
http://denis.usj.es/web/wp-content/uploads/2017/06/carro2016.pdf},
doi = {10.1016/j.pbiomolbio.2016.11.006},
issn = {0079-6107},
year = {2017},
date = {2017-10-01},
journal = {Progress in Biophysics and Molecular Biology},
volume = {129},
pages = {53-64},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
Martín-Yebra, A; Monasterio, V; Cygankiewicz, I; Bayés de Luna, A; Caiani, E G; Laguna, P; Martínez, J P Post-ventricular premature contraction phase correction improves the predictive value of average T-wave alternans in ambulatory ECG recordings IEEE Transactions Biomedical Engineering, 65 (3), pp. 635–644, 2017. Links | BibTeX @article{MartinYebra2017,
title = {Post-ventricular premature contraction phase correction improves the predictive value of average T-wave alternans in ambulatory ECG recordings},
author = {Martín-Yebra, A. and Monasterio, V. and Cygankiewicz, I. and Bayés de Luna, A. and Caiani, E. G. and Laguna, P. and Martínez, J. P. },
url = {https://denis.usj.es/wp-content/uploads/2018/10/AlternanciasEctopicosAlba.pdf},
doi = {10.1109/TBME.2017.2711645},
year = {2017},
date = {2017-06-02},
journal = {IEEE Transactions Biomedical Engineering},
volume = {65},
number = {3},
pages = {635--644},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
Ramírez, J; Orini, M; Mincholé, A; Monasterio, V; Cygankiewicz, I; Bayés de Luna, A; Martínez, J P; Pueyo, E; Laguna, P T-Wave Morphology Restitution Predicts Sudden Cardiac Death in Patients With Chronic Heart Failure Journal of the American Heart Association, 6 (5), 2017, ISSN: 2047-9980. Abstract | Links | BibTeX @article{Ramirez2017,
title = {T-Wave Morphology Restitution Predicts Sudden Cardiac Death in Patients With Chronic Heart Failure},
author = {Ramírez, J. and Orini, M. and Mincholé, A. and Monasterio, V. and Cygankiewicz, I. and Bayés de Luna, A. and Martínez, J.P. and Pueyo, E. and Laguna, P.},
url = {http://jaha.ahajournals.org/content/6/5/e005310},
doi = {10.1161/JAHA.116.005310},
issn = {2047-9980},
year = {2017},
date = {2017-01-01},
journal = {Journal of the American Heart Association},
volume = {6},
number = {5},
publisher = {American Heart Association, Inc.},
abstract = {Background Patients with chronic heart failure are at high risk of sudden cardiac death (SCD). Increased dispersion of repolarization restitution has been associated with SCD, and we hypothesize that this should be reflected in the morphology of the T-wave and its variations with heart rate. The aim of this study is to propose an electrocardiogram (ECG)-based index characterizing T-wave morphology restitution (TMR), and to assess its association with SCD risk in a population of chronic heart failure patients.Methods and Results Holter ECGs from 651 ambulatory patients with chronic heart failure from the MUSIC (MUerte S'ubita en Insuficiencia Cardiaca) study were available for the analysis. TMR was quantified by measuring the morphological variation of the T-wave per RR increment using time-warping metrics, and its predictive power was compared to that of clinical variables such as the left ventricular ejection fraction and other ECG-derived indices, such as T-wave alternans and heart rate variability. TMR was significantly higher in SCD victims than in the rest of patients (median 0.046 versus 0.039, P<0.001). When TMR was dichotomized at TMR=0.040, the SCD rate was significantly higher in the TMR>=0.040 group (P<0.001). Cox analysis revealed that TMR>=0.040 was strongly associated with SCD, with a hazard ratio of 3.27 (P<0.001), independently of clinical and ECG-derived variables. No association was found between TMR and pump failure death.Conclusions This study shows that TMR is specifically associated with SCD in a population of chronic heart failure patients, and it is a better predictor than clinical and ECG-derived variables.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Background Patients with chronic heart failure are at high risk of sudden cardiac death (SCD). Increased dispersion of repolarization restitution has been associated with SCD, and we hypothesize that this should be reflected in the morphology of the T-wave and its variations with heart rate. The aim of this study is to propose an electrocardiogram (ECG)-based index characterizing T-wave morphology restitution (TMR), and to assess its association with SCD risk in a population of chronic heart failure patients.Methods and Results Holter ECGs from 651 ambulatory patients with chronic heart failure from the MUSIC (MUerte S'ubita en Insuficiencia Cardiaca) study were available for the analysis. TMR was quantified by measuring the morphological variation of the T-wave per RR increment using time-warping metrics, and its predictive power was compared to that of clinical variables such as the left ventricular ejection fraction and other ECG-derived indices, such as T-wave alternans and heart rate variability. TMR was significantly higher in SCD victims than in the rest of patients (median 0.046 versus 0.039, P<0.001). When TMR was dichotomized at TMR=0.040, the SCD rate was significantly higher in the TMR>=0.040 group (P<0.001). Cox analysis revealed that TMR>=0.040 was strongly associated with SCD, with a hazard ratio of 3.27 (P<0.001), independently of clinical and ECG-derived variables. No association was found between TMR and pump failure death.Conclusions This study shows that TMR is specifically associated with SCD in a population of chronic heart failure patients, and it is a better predictor than clinical and ECG-derived variables. |
Carro, J; Rodríguez Matas, J F; Pueyo, E A Methodology to Improve Human Ventricular Models for the Investigation of Cardiac Arrhythmias Biophysical Journal, 112 (3, Supplement 1), pp. 403a, Published in abstract form, 2017, ISSN: 0006-3495. Links | BibTeX @article{Carro2017a,
title = {A Methodology to Improve Human Ventricular Models for the Investigation of Cardiac Arrhythmias},
author = {Carro, J. and Rodríguez Matas, J.F. and Pueyo, E.},
url = {http://denis.usj.es/web/wp-content/uploads/2017/06/carro2017a.pdf},
doi = {http://dx.doi.org/10.1016/j.bpj.2016.11.2183},
issn = {0006-3495},
year = {2017},
date = {2017-01-01},
journal = {Biophysical Journal},
volume = {112},
number = {3, Supplement 1},
pages = {403a, Published in abstract form},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
Inproceedings
|
Martín-Yebra, A; Monasterio, V; Laguna, P; Martínez, J P; Caiani, E G Evaluation of Changes in T-wave Alternans Induced by 60-days of Immobilization by Head-Down Bed-Rest Proceedings of the XLIV International Conference on Computing in Cardiology. Rennes, France, pp. 1-4, 2017. Links | BibTeX @inproceedings{MartinYebra2017b,
title = {Evaluation of Changes in T-wave Alternans Induced by 60-days of Immobilization by Head-Down Bed-Rest},
author = {Martín-Yebra, A. and Monasterio, V. and Laguna, P. and Martínez, J.P. and Caiani, E.G.},
doi = {10.22489/CinC.2017.038-430},
year = {2017},
date = {2017-09-01},
booktitle = {Proceedings of the XLIV International Conference on Computing in Cardiology. Rennes, France},
pages = {1-4},
keywords = {},
pubstate = {published},
tppubtype = {inproceedings}
}
|
Conferences
|
Carro, J; Rodríguez Matas, J F; Pueyo, E Multiscale Methods for Definition of Ionic Variables in Electrophysiological Models EMBEC 2017, NBC 2017, Abstracts Book pp. 115, 2017. Links | BibTeX @conference{Carro2017c,
title = {Multiscale Methods for Definition of Ionic Variables in Electrophysiological Models},
author = {Carro, J. and Rodríguez Matas, J.F. and Pueyo, E.},
url = {http://denis.usj.es/wp-content/uploads/2017/11/EMBEC-NBC-17-Jesus.pdf},
year = {2017},
date = {2017-06-12},
booktitle = {EMBEC 2017, NBC 2017, Abstracts Book pp. 115},
keywords = {},
pubstate = {published},
tppubtype = {conference}
}
|
2016
|
Inproceedings
|
García-Escolano, A; Mora, M T; Monasterio, V; Rodríguez, J F; Ferrero, J M Estudio mediante modelado y simulación del efecto de la isquemia miocárdica aguda en las fibras de Purkinje de corazón humano Proceedings XXXIV Congreso Anual de la Sociedad Española de Ingeniería Biomédica, pp. 471-474, 2016, ISBN: 978-84-9048-531-6. Links | BibTeX @inproceedings{GarciaEscolano2017,
title = { Estudio mediante modelado y simulación del efecto de la isquemia miocárdica aguda en las fibras de Purkinje de corazón humano},
author = {García-Escolano, A. and Mora, M.T. and Monasterio, V. and Rodríguez, J.F. and Ferrero, J.M.},
url = {https://denis.usj.es/wp-content/uploads/2018/10/caseib16Violeta.pdf},
isbn = {978-84-9048-531-6},
year = {2016},
date = {2016-11-25},
booktitle = {Proceedings XXXIV Congreso Anual de la Sociedad Española de Ingeniería Biomédica},
pages = {471-474},
keywords = {},
pubstate = {published},
tppubtype = {inproceedings}
}
|
Castro, J; Monasterio, V; Carro, J Volunteer Computing Approach for the Collaborative Simulation of Electrophysiological Models 2016 IEEE 25th International Conference on Enabling Technologies: Infrastructure for Collaborative Enterprises (WETICE), pp. 118-123, 2016. Links | BibTeX @inproceedings{Castro2016,
title = {Volunteer Computing Approach for the Collaborative Simulation of Electrophysiological Models},
author = {Castro, J. and Monasterio, V. and Carro, J.},
url = {http://denis.usj.es/web/wp-content/uploads/2017/07/castro2016.pdf},
doi = {10.1109/WETICE.2016.34},
year = {2016},
date = {2016-06-01},
booktitle = {2016 IEEE 25th International Conference on Enabling Technologies: Infrastructure for Collaborative Enterprises (WETICE)},
pages = {118-123},
keywords = {},
pubstate = {published},
tppubtype = {inproceedings}
}
|
Marcén, A C; Carro, J; Monasterio, V Wearable Monitoring for the Detection of Nocturnal Agitation in Dementia Proceedings of the 6th International Joint Conference on Pervasive and Embedded Computing and Communication Systems, pp. 63-69, 2016, ISBN: 978-989-758-195-3. Links | BibTeX @inproceedings{Marcen2016,
title = {Wearable Monitoring for the Detection of Nocturnal Agitation in Dementia},
author = {Marcén, A.C. and Carro, J. and Monasterio, V.},
doi = {10.5220/0005938500630069},
isbn = {978-989-758-195-3},
year = {2016},
date = {2016-01-01},
booktitle = {Proceedings of the 6th International Joint Conference on Pervasive and Embedded Computing and Communication Systems},
pages = {63-69},
keywords = {},
pubstate = {published},
tppubtype = {inproceedings}
}
|
2015
|
Journal Articles
|
Martin-Yebra, A; Caiani, E; Monasterio, V; Pellegrini, A; Laguna, P; Martinez, J P Evaluation of T-wave alternans activity under stress conditions after 5 days and 21 days of sedentary head-down bed-rest Physiological measurement, 36 , pp. 2041–2055, 2015. Links | BibTeX @article{MartinYebra2015b,
title = {Evaluation of T-wave alternans activity under stress conditions after 5 days and 21 days of sedentary head-down bed-rest},
author = {Martin-Yebra, A. and Caiani, E. and Monasterio, V. and Pellegrini, A. and Laguna, P. and Martinez, J.P.},
url = {https://denis.usj.es/wp-content/uploads/2018/10/AlternansESA-Alba.pdf},
doi = {10.1088/0967-3334/36/10/2041},
year = {2015},
date = {2015-08-19},
journal = {Physiological measurement},
volume = {36},
pages = {2041--2055},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
Ramírez, J; Monasterio, V; Mincholé, A; Llamedo, M; Lenis, G; Cygankiewicz, I; Bayés De Luna, A; Malik, M; Martínez, J P; Laguna, P; Pueyo, E Automatic SVM classification of sudden cardiac death and pump failure death from autonomic and repolarization ECG markers Journal of Electrocardiology, 48 (4), pp. 551-557, 2015. Links | BibTeX @article{Ramirez2015,
title = {Automatic SVM classification of sudden cardiac death and pump failure death from autonomic and repolarization ECG markers},
author = {Ramírez, J. and Monasterio, V. and Mincholé, A. and Llamedo, M. and Lenis, G. and Cygankiewicz, I. and Bayés De Luna, A. and Malik, M. and Martínez, J.P. and Laguna, P. and Pueyo, E.},
url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-84937730461&partnerID=40&md5=dc33b31b3016579b83ac44fcb718ebf1},
doi = {10.1016/j.jelectrocard.2015.04.002},
year = {2015},
date = {2015-01-01},
journal = {Journal of Electrocardiology},
volume = {48},
number = {4},
pages = {551-557},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
Conferences
|
Carro, J; Rodríguez Matas, J F; Pueyo, E A Response Surface Optimization approach to adjust ionic current conductances of cardiac electrophysiological models Cardiac Arrhythmia Mechanisms 2015, Lucca (Italy), 2015. BibTeX @conference{Carro2015,
title = {A Response Surface Optimization approach to adjust ionic current conductances of cardiac electrophysiological models },
author = {Carro, J. and Rodríguez Matas, J.F. and Pueyo, E.},
year = {2015},
date = {2015-03-27},
booktitle = {Cardiac Arrhythmia Mechanisms 2015, Lucca (Italy)},
keywords = {},
pubstate = {published},
tppubtype = {conference}
}
|
Inproceedings
|
Martín Yebra, A; Caiani, E G; Laguna, P; Monasterio, V; Martínez, J P Circadian Modulation on T-wave Alternans Activity in Chronic Heart Failure Patients Computing in Cardiology, pp. 845-848, 2015. BibTeX @inproceedings{MartinYebra2015,
title = {Circadian Modulation on T-wave Alternans Activity in Chronic Heart Failure Patients},
author = {Martín Yebra, A. and Caiani, E.G. and Laguna, P. and Monasterio, V. and Martínez, J.P.},
year = {2015},
date = {2015-01-01},
booktitle = {Computing in Cardiology},
volume = {42},
pages = {845-848},
keywords = {},
pubstate = {published},
tppubtype = {inproceedings}
}
|
Monasterio, V; Carro, J; Rodríguez Matas, J F; Pueyo, E The Role of Purkinje Automaticity as an Arrhythmia Mechanism in Hyperkalaemia Computing in Cardiology, pp. 873-876, 2015. Links | BibTeX @inproceedings{Monasterio2015,
title = {The Role of Purkinje Automaticity as an Arrhythmia Mechanism in Hyperkalaemia},
author = {Monasterio, V. and Carro, J. and Rodríguez Matas, J.F. and Pueyo, E.},
doi = {10.1109/CIC.2015.7411050},
year = {2015},
date = {2015-01-01},
booktitle = {Computing in Cardiology},
volume = {42},
pages = {873-876},
keywords = {},
pubstate = {published},
tppubtype = {inproceedings}
}
|
2014
|
Inproceedings
|
Carro, J; Rodríguez Matas, J F; Pueyo, E In silico simulations of experimental protocols for cardiac modeling Engineering in Medicine and Biology Society (EMBC), 2014 36th Annual International Conference of the IEEE, pp. 5695-5698, 2014, ISSN: 1557-170X. Links | BibTeX @inproceedings{Carro2014,
title = {In silico simulations of experimental protocols for cardiac modeling},
author = {Carro, J. and Rodríguez Matas, J.F. and Pueyo, E.},
url = {http://dx.doir.org/10.1109/EMBC.2014.6944920},
doi = {10.1109/EMBC.2014.6944920},
issn = {1557-170X},
year = {2014},
date = {2014-08-01},
booktitle = {Engineering in Medicine and Biology Society (EMBC), 2014 36th Annual International Conference of the IEEE},
pages = {5695-5698},
keywords = {},
pubstate = {published},
tppubtype = {inproceedings}
}
|
Martín Yebra, A; Caiani, E G; Monasterio, V; Pellegrini, A; Laguna, P; Martínez, J P T-wave alternans and autonomic nervous system activity during orthostatic stress after 5 days of head-down bed-rest 2014 8th Conference of the European Study Group on Cardiovascular Oscillations, ESGCO 2014, pp. 115-116, 2014. Links | BibTeX @inproceedings{MartinYebra2014,
title = {T-wave alternans and autonomic nervous system activity during orthostatic stress after 5 days of head-down bed-rest},
author = {Martín Yebra, A. and Caiani, E.G. and Monasterio, V. and Pellegrini, A. and Laguna, P. and Martínez, J.P.},
url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-84904500596&partnerID=40&md5=50aac4925658d1dc6be337db6860227b},
doi = {10.1109/ESGCO.2014.6847546},
year = {2014},
date = {2014-01-01},
booktitle = {2014 8th Conference of the European Study Group on Cardiovascular Oscillations, ESGCO 2014},
pages = {115-116},
keywords = {},
pubstate = {published},
tppubtype = {inproceedings}
}
|
Monasterio, V; Carro, J; Pueyo, E Repolarization alternans in human ventricular hyperkalaemic tissue: dependence on current stimulation XXXII Congreso Anual de la Sociedad Española de Ingeniería Biomédica, Barcelona, pp. 1-4, 2014, ISBN: 9788461724468. BibTeX @inproceedings{Monasterio2014,
title = {Repolarization alternans in human ventricular hyperkalaemic tissue: dependence on current stimulation},
author = {Monasterio, V. and Carro, J. and Pueyo, E.},
isbn = {9788461724468},
year = {2014},
date = {2014-01-01},
booktitle = {XXXII Congreso Anual de la Sociedad Española de Ingeniería Biomédica, Barcelona},
pages = {1-4},
keywords = {},
pubstate = {published},
tppubtype = {inproceedings}
}
|
Journal Articles
|
Orini, M; Hanson, B; Monasterio, V; Martínez, J P; Hayward, M; Taggart, P; Lambiase, P Comparative evaluation of methodologies for T-wave alternans mapping in electrograms IEEE Transactions on Biomedical Engineering, 61 (2), pp. 308-316, 2014. Links | BibTeX @article{Orini2014,
title = {Comparative evaluation of methodologies for T-wave alternans mapping in electrograms},
author = {Orini, M. and Hanson, B. and Monasterio, V. and Martínez, J.P. and Hayward, M. and Taggart, P. and Lambiase, P.},
url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-84893213627&partnerID=40&md5=01226c890c5bf30d4e5dae3a8a9bdf2b},
doi = {10.1109/TBME.2013.2289304},
year = {2014},
date = {2014-01-01},
journal = {IEEE Transactions on Biomedical Engineering},
volume = {61},
number = {2},
pages = {308-316},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
Roebuck, A; Monasterio, V; Gederi, E; Osipov, M; Behar, J; Malhotra, A; Penzel, T; Clifford, G D A review of signals used in sleep analysis Physiological Measurement, 35 (1), pp. R1-R57, 2014. Links | BibTeX @article{Roebuck2014,
title = {A review of signals used in sleep analysis},
author = {Roebuck, A. and Monasterio, V. and Gederi, E. and Osipov, M. and Behar, J. and Malhotra, A. and Penzel, T. and Clifford, G.D.},
url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-84891330537&partnerID=40&md5=158dcab62f5dfed3a7fb25d3e8c9a5cd},
doi = {10.1088/0967-3334/35/1/R1},
year = {2014},
date = {2014-01-01},
journal = {Physiological Measurement},
volume = {35},
number = {1},
pages = {R1-R57},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
2013
|
Journal Articles
|
Demidova, M M; Martín Yebra, A; Martínez, J P; Monasterio, V; Koul, S; Van Der Pals, J; Romero, D; Laguna, P; Erlinge, D; Platonov, P G T wave alternans in experimental myocardial infarction: Time course and predictive value for the assessment of myocardial damage Journal of Electrocardiology, 46 (3), pp. 263-269, 2013. Links | BibTeX @article{Demidova2013,
title = {T wave alternans in experimental myocardial infarction: Time course and predictive value for the assessment of myocardial damage},
author = {Demidova, M.M. and Martín Yebra, A. and Martínez, J.P. and Monasterio, V. and Koul, S. and Van Der Pals, J. and Romero, D. and Laguna, P. and Erlinge, D. and Platonov, P.G.},
url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-84876675340&partnerID=40&md5=5cb49cdc2a3dc11ad70914f79f17c6c2},
doi = {10.1016/j.jelectrocard.2013.03.001},
year = {2013},
date = {2013-01-01},
journal = {Journal of Electrocardiology},
volume = {46},
number = {3},
pages = {263-269},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
Monasterio, V; Martínez, J P; Laguna, P; McNitt, S; Polonsky, S; Moss, A J; Haigney, M; Zareba, W; Couderc, J P Prognostic value of average T-wave alternans and QT variability for cardiac events in MADIT-II patients Journal of Electrocardiology, 46 (6), pp. 480-486, 2013. Links | BibTeX @article{Monasterio2013b,
title = {Prognostic value of average T-wave alternans and QT variability for cardiac events in MADIT-II patients},
author = {Monasterio, V. and Martínez, J.P. and Laguna, P. and McNitt, S. and Polonsky, S. and Moss, A.J. and Haigney, M. and Zareba, W. and Couderc, J.P.},
url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-84886954199&partnerID=40&md5=335898cd788445dd2f75b2040c9b0f96},
doi = {10.1016/j.jelectrocard.2013.08.004},
year = {2013},
date = {2013-01-01},
journal = {Journal of Electrocardiology},
volume = {46},
number = {6},
pages = {480-486},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
Inproceedings
|
Monasterio, V; Martinez, J P; McNitt, S; Laguna, P; Moss, A J; Zareba, W; Couderc, J P T-wave alternans predicts ICD discharge in MADIT II patients with elevated resting heart rate Computing in Cardiology, pp. 603-606, 2013. Links | BibTeX @inproceedings{Monasterio2013a,
title = {T-wave alternans predicts ICD discharge in MADIT II patients with elevated resting heart rate},
author = {Monasterio, V. and Martinez, J.P. and McNitt, S. and Laguna, P. and Moss, A.J. and Zareba, W. and Couderc, J.P.},
url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-84894176323&partnerID=40&md5=c068606ef62fe1366ecc2c3992a6e55f},
year = {2013},
date = {2013-01-01},
booktitle = {Computing in Cardiology},
volume = {40},
pages = {603-606},
keywords = {},
pubstate = {published},
tppubtype = {inproceedings}
}
|
2012
|
Inproceedings
|
Daly, J; Monasterio, V; Clifford, G D A neonatal apnoea monitor for resource-constrained environments Computing in Cardiology, pp. 321-324, 2012. Links | BibTeX @inproceedings{Daly2012,
title = {A neonatal apnoea monitor for resource-constrained environments},
author = {Daly, J. and Monasterio, V. and Clifford, G.D.},
url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-84875686618&partnerID=40&md5=bd7bf1c824f1af2eaa5b715e48959c86},
year = {2012},
date = {2012-01-01},
booktitle = {Computing in Cardiology},
volume = {39},
pages = {321-324},
keywords = {},
pubstate = {published},
tppubtype = {inproceedings}
}
|
Martin Yebra, A; Monasterio, V; Pellegrini, A; Laguna, P; Caiani, E G; Martinez, J P Effect of simulated microgravity by head-down bed rest on T wave alternans Computing in Cardiology, pp. 377-380, 2012. Links | BibTeX @inproceedings{MartinYebra2012,
title = {Effect of simulated microgravity by head-down bed rest on T wave alternans},
author = {Martin Yebra, A. and Monasterio, V. and Pellegrini, A. and Laguna, P. and Caiani, E.G. and Martinez, J.P.},
url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-84875656961&partnerID=40&md5=8e35144e6d102b50dd75a8a893d6867c},
year = {2012},
date = {2012-01-01},
booktitle = {Computing in Cardiology},
volume = {39},
pages = {377-380},
keywords = {},
pubstate = {published},
tppubtype = {inproceedings}
}
|
Journal Articles
|
Monasterio, V; Burgess, F; Clifford, G D Robust classification of neonatal apnoea-related desaturations Physiological Measurement, 33 (9), pp. 1503-1516, 2012. Links | BibTeX @article{Monasterio2012a,
title = {Robust classification of neonatal apnoea-related desaturations},
author = {Monasterio, V. and Burgess, F. and Clifford, G.D.},
url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-84866318050&partnerID=40&md5=6e245123027bf3c04b16ac1354a42fc3},
doi = {10.1088/0967-3334/33/9/1503},
year = {2012},
date = {2012-01-01},
journal = {Physiological Measurement},
volume = {33},
number = {9},
pages = {1503-1516},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
Monasterio, V; Laguna, P; Cygankiewicz, I; Vázquez, R; Bayés-Genís, A; Bayés De Luna, A; Martínez, J P Average T-wave alternans activity in ambulatory ECG records predicts sudden cardiac death in patients with chronic heart failure Heart Rhythm, 9 (3), pp. 383-389, 2012. Links | BibTeX @article{Monasterio2012b,
title = {Average T-wave alternans activity in ambulatory ECG records predicts sudden cardiac death in patients with chronic heart failure},
author = {Monasterio, V. and Laguna, P. and Cygankiewicz, I. and Vázquez, R. and Bayés-Genís, A. and Bayés De Luna, A. and Martínez, J.P.},
url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-84857644866&partnerID=40&md5=6a1ab7e16daba9776581766782abe1ff},
doi = {10.1016/j.hrthm.2011.10.027},
year = {2012},
date = {2012-01-01},
journal = {Heart Rhythm},
volume = {9},
number = {3},
pages = {383-389},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
Rodríguez Matas, J F; Carro, J; Pueyo, E; Burrage, K; Rodríguez, B Impact of Multiple Ionic Changes in Arrhythmic Risk Biomarkers in Human Ventricular Electrophysiology Biophysical Journal, 102 (3), pp. 543-543, Published in abstract form, 2012. Links | BibTeX @article{Rodriguez2012,
title = {Impact of Multiple Ionic Changes in Arrhythmic Risk Biomarkers in Human Ventricular Electrophysiology},
author = {Rodríguez Matas, J.F. and Carro, J. and Pueyo, E. and Burrage, K. and Rodríguez, B.},
url = {http://dx.doi.org/10.1016/j.bpj.2011.11.2965},
doi = {10.1016/j.bpj.2011.11.2965},
year = {2012},
date = {2012-01-01},
journal = {Biophysical Journal},
volume = {102},
number = {3},
pages = {543-543, Published in abstract form},
publisher = {Biophysical Journal},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
2011
|
PhD Theses
|
Monasterio, V Multilead analysis of T-wave alternans in the electrocardiogram University of Zaragoza, 2011. BibTeX @phdthesis{MonasterioTesis,
title = {Multilead analysis of T-wave alternans in the electrocardiogram},
author = {Monasterio, V.},
year = {2011},
date = {2011-06-01},
address = {Zaragoza, SPAIN},
school = {University of Zaragoza},
keywords = {},
pubstate = {published},
tppubtype = {phdthesis}
}
|
Journal Articles
|
Carro, J; Rodríguez Matas, J F; Laguna, P; Pueyo, E A human ventricular cell model for investigation of cardiac arrhythmias under hyperkalaemic conditions Philosophical Transactions of the Royal Society of London A: Mathematical, Physical and Engineering Sciences, 369 (1954), pp. 4205–4232, 2011. Links | BibTeX @article{Carro2011,
title = {A human ventricular cell model for investigation of cardiac arrhythmias under hyperkalaemic conditions},
author = {Carro, J. and Rodríguez Matas, J.F. and Laguna, P. and Pueyo, E.},
url = {http://dx.doi.org/10.1098/rsta.2011.0127},
doi = {10.1098/rsta.2011.0127},
year = {2011},
date = {2011-01-01},
journal = {Philosophical Transactions of the Royal Society of London A: Mathematical, Physical and Engineering Sciences},
volume = {369},
number = {1954},
pages = {4205--4232},
publisher = {The Royal Society},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
Nemati, S; Abdala, O; Monasterio, V; Yim-Yeh, S; Malhotra, A; Clifford, G D A nonparametric surrogate-based test of significance for T-wave alternans detection IEEE Transactions on Biomedical Engineering, 58 (5), pp. 1356-1364, 2011. Links | BibTeX @article{Nemati2011,
title = {A nonparametric surrogate-based test of significance for T-wave alternans detection},
author = {Nemati, S. and Abdala, O. and Monasterio, V. and Yim-Yeh, S. and Malhotra, A. and Clifford, G.D.},
url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-79955532916&partnerID=40&md5=c4aece2944a93cc05871f85b49ce506a},
doi = {10.1109/TBME.2010.2047859},
year = {2011},
date = {2011-01-01},
journal = {IEEE Transactions on Biomedical Engineering},
volume = {58},
number = {5},
pages = {1356-1364},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
Inproceedings
|
Martínez, J P; Martín Yebra, A; Monasterio, V; Demidova, M M; Platonov, P G; Laguna, P Time course and spatial distribution of T wave alternans induced by coronary artery occlusion in pigs Computing in Cardiology, pp. 669-672, 2011. Links | BibTeX @inproceedings{Martinez2011,
title = {Time course and spatial distribution of T wave alternans induced by coronary artery occlusion in pigs},
author = {Martínez, J.P. and Martín Yebra, A. and Monasterio, V. and Demidova, M.M. and Platonov, P.G. and Laguna, P.},
url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-84859947474&partnerID=40&md5=a491cf5adb92516a163920b065364e63},
year = {2011},
date = {2011-01-01},
booktitle = {Computing in Cardiology},
volume = {38},
pages = {669-672},
keywords = {},
pubstate = {published},
tppubtype = {inproceedings}
}
|
Monasterio, V; Laguna, P; Cygankiewicz, I; Martínez, J P Average T-wave alternans activity in ambulatory ECGs Computing in Cardiology, pp. 621-624, 2011. Links | BibTeX @inproceedings{Monasterio2011,
title = {Average T-wave alternans activity in ambulatory ECGs},
author = {Monasterio, V. and Laguna, P. and Cygankiewicz, I. and Martínez, J.P.},
url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-84859948290&partnerID=40&md5=1cb4b184b3a2e77d8d44af5803adbd13},
year = {2011},
date = {2011-01-01},
booktitle = {Computing in Cardiology},
volume = {38},
pages = {621-624},
keywords = {},
pubstate = {published},
tppubtype = {inproceedings}
}
|
2010
|
Masters Theses
|
Carro, J An Improved Human Ventricular Cell Model for Investigation of Cardiac Arrhythmias under Hyperkalemic Conditions University of Zaragoza, 2010. Links | BibTeX @mastersthesis{Carro2010MT,
title = {An Improved Human Ventricular Cell Model for Investigation of Cardiac Arrhythmias under Hyperkalemic Conditions},
author = {Carro, J.},
url = {https://zaguan.unizar.es/record/5430?ln=en},
year = {2010},
date = {2010-12-01},
address = {University of Zaragoza, SPAIN},
school = {University of Zaragoza},
keywords = {},
pubstate = {published},
tppubtype = {mastersthesis}
}
|
Inproceedings
|
Carro, J; Rodríguez Matas, J F; Laguna, P; Pueyo, E Analysis and improvement of a human ventricular cell model for investigation of cardiac arrhythmias Computing in Cardiology, 2010, pp. 817-820, 2010, ISSN: 0276-6547. Links | BibTeX @inproceedings{Carro2010,
title = {Analysis and improvement of a human ventricular cell model for investigation of cardiac arrhythmias},
author = {Carro, J. and Rodríguez Matas, J.F. and Laguna, P. and Pueyo, E.},
url = {http://ieeexplore.ieee.org/document/5738098/},
issn = {0276-6547},
year = {2010},
date = {2010-09-01},
booktitle = {Computing in Cardiology, 2010},
pages = {817-820},
keywords = {},
pubstate = {published},
tppubtype = {inproceedings}
}
|
Monasterio, V; Clifford, G D; Martínez, J P Comparison of source separation techniques for multilead T-wave alternans detection in the ECG 2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10, pp. 5367-5370, 2010. Links | BibTeX @inproceedings{Monasterio2010a,
title = {Comparison of source separation techniques for multilead T-wave alternans detection in the ECG},
author = {Monasterio, V. and Clifford, G.D. and Martínez, J.P.},
url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-78650840530&partnerID=40&md5=c5a71c1f7365428992682cc9cfd7345a},
doi = {10.1109/IEMBS.2010.5626356},
year = {2010},
date = {2010-01-01},
booktitle = {2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10},
pages = {5367-5370},
keywords = {},
pubstate = {published},
tppubtype = {inproceedings}
}
|
Journal Articles
|
Monasterio, V; Clifford, G D; Laguna, P; Martínez, J P A multilead scheme based on periodic component analysis for T-Wave alternans analysis in the ECG Annals of Biomedical Engineering, 38 (8), pp. 2532-2541, 2010. Links | BibTeX @article{Monasterio2010b,
title = {A multilead scheme based on periodic component analysis for T-Wave alternans analysis in the ECG},
author = {Monasterio, V. and Clifford, G.D. and Laguna, P. and Martínez, J.P.},
url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-77955175298&partnerID=40&md5=326e91fd2f21e0c6f4d8a61ef1ea317b},
doi = {10.1007/s10439-010-0029-z},
year = {2010},
date = {2010-01-01},
journal = {Annals of Biomedical Engineering},
volume = {38},
number = {8},
pages = {2532-2541},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
2009
|
Inproceedings
|
Monasterio, V; Martínez, J P Comparison of two eigenvalue decomposition techniques to detect T wave alternans in the ECG IFMBE Proceedings, pp. 631-634, 2009. Links | BibTeX @inproceedings{Monasterio2009a,
title = {Comparison of two eigenvalue decomposition techniques to detect T wave alternans in the ECG},
author = {Monasterio, V. and Martínez, J.P.},
url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-77950112946&partnerID=40&md5=02dda5fb27e1bbcfa52ca643c6029aaf},
doi = {10.1007/978-3-642-03882-2-168},
year = {2009},
date = {2009-01-01},
booktitle = {IFMBE Proceedings},
volume = {25},
number = {4},
pages = {631-634},
keywords = {},
pubstate = {published},
tppubtype = {inproceedings}
}
|
Journal Articles
|
Monasterio, V; Laguna, P; Martínez, J P Multilead analysis of T-wave alternans in the ecg using principal component analysis IEEE Transactions on Biomedical Engineering, 56 (7), pp. 1880-1890, 2009. Links | BibTeX @article{Monasterio2009b,
title = {Multilead analysis of T-wave alternans in the ecg using principal component analysis},
author = {Monasterio, V. and Laguna, P. and Martínez, J.P.},
url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-67650868981&partnerID=40&md5=a5771107d61106828be0b98727161405},
doi = {10.1109/TBME.2009.2015935},
year = {2009},
date = {2009-01-01},
journal = {IEEE Transactions on Biomedical Engineering},
volume = {56},
number = {7},
pages = {1880-1890},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
2008
|
Masters Theses
|
Monasterio, V Análisis multiderivacional de alternancias de onda T en el ECG University of Zaragoza, 2008. BibTeX @mastersthesis{MonasterioMT,
title = {Análisis multiderivacional de alternancias de onda T en el ECG},
author = {Monasterio, V.},
year = {2008},
date = {2008-09-01},
address = {University of Zaragoza, SPAIN},
school = {University of Zaragoza},
keywords = {},
pubstate = {published},
tppubtype = {mastersthesis}
}
|
Inproceedings
|
Monasterio, V; Martínez, J P Multilead T-Wave Alternans quantification based on spatial filtering and the Laplacian likelihood ratio method Computers in Cardiology, pp. 601-604, 2008. Links | BibTeX @inproceedings{Monasterio2008a,
title = {Multilead T-Wave Alternans quantification based on spatial filtering and the Laplacian likelihood ratio method},
author = {Monasterio, V. and Martínez, J.P.},
url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-62249222097&partnerID=40&md5=f17e6919855d46a1073aba1993f2f64e},
doi = {10.1109/CIC.2008.4749113},
year = {2008},
date = {2008-01-01},
booktitle = {Computers in Cardiology},
volume = {35},
pages = {601-604},
keywords = {},
pubstate = {published},
tppubtype = {inproceedings}
}
|
Monasterio, V; Laguna, P; Martínez, J P Multilead estimation of T-wave alternans in the ECG using principal component analysis European Signal Processing Conference, 2008. Links | BibTeX @inproceedings{Monasterio2008b,
title = {Multilead estimation of T-wave alternans in the ECG using principal component analysis},
author = {Monasterio, V. and Laguna, P. and Martínez, J.P.},
url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-84863740465&partnerID=40&md5=deea10d9384e75441c316288a65ae434},
year = {2008},
date = {2008-01-01},
booktitle = {European Signal Processing Conference},
keywords = {},
pubstate = {published},
tppubtype = {inproceedings}
}
|
2007
|
Inproceedings
|
Monasterio, V; Martínez, J P A multilead approach to T-wave alternans detection combining principal component analysis and the laplacian ikelihood ratio method Computers in Cardiology, pp. 5-8, 2007. Links | BibTeX @inproceedings{Monasterio2007,
title = {A multilead approach to T-wave alternans detection combining principal component analysis and the laplacian ikelihood ratio method},
author = {Monasterio, V. and Martínez, J.P.},
url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-62249094943&partnerID=40&md5=5f0f715e13f2670f2bee6ff2cbad8a51},
doi = {10.1109/CIC.2007.4745407},
year = {2007},
date = {2007-01-01},
booktitle = {Computers in Cardiology},
volume = {34},
pages = {5-8},
keywords = {},
pubstate = {published},
tppubtype = {inproceedings}
}
|
2005
|
Inproceedings
|
Gil, E; Monasterio, V; Laguna, P; Vergara, J M Pulse photopletismography amplitude decrease detector for sleep apnea evaluation in children Annual International Conference of the IEEE Engineering in Medicine and Biology, pp. 2743-2746, 2005. Links | BibTeX @inproceedings{Gil2005,
title = {Pulse photopletismography amplitude decrease detector for sleep apnea evaluation in children},
author = {Gil, E. and Monasterio, V. and Laguna, P. and Vergara, J.M.},
url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-33846934771&partnerID=40&md5=773aee57208d2d56d270271b72bfed00},
year = {2005},
date = {2005-01-01},
booktitle = {Annual International Conference of the IEEE Engineering in Medicine and Biology},
volume = {7 VOLS},
pages = {2743-2746},
keywords = {},
pubstate = {published},
tppubtype = {inproceedings}
}
|
