DENIS Natrium (version 2)

The second stable version of DENIS Simulator is called Natrium, it’s an evolution of Kalium version. It solves the same models, but the configuration files are different.

Natrium configuration files got XML format that makes them more human readable. The input parameters are similar to Kalium:

  • The model that will simulate
  • The length of the simulation
  • The differential time used for simulate
  • The marker that will looking for
  • Constants to change and it’s value
  • The output frequency to store values
  • The time to start the capture of the simulation
  • The states that will be saved at result files
  • The algebraic that will be saved at result files

Natrium have also the capacity to find markers in the simulation, the parameter to find the is stored at configuration files and will generate a different result file to store all the markers on the simulation.

The markers that will be saved in the markers file will be:

  • APD 90, 75,50,25 and 10
  • The time that starts the APD
  • The maximum and the minimum value
  • The maximun and the minimum difference

Those electrophysiological markers are always computed in cardiac simulations. In order to facilitate that scientists can reuse and share them, the results are stored in a No-SQL database. This information can be also used to calibrate model populations.

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